PUS10
-
Official Full Name
pseudouridylate synthase 10 -
Overview
Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide;modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate;synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing;RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs (McCleverty et;al., 2007 (PubMed 17900615)). -
Synonyms
PUS10;pseudouridylate synthase 10;CCDC139, coiled coil domain containing 139;putative tRNA pseudouridine synthase Pus10;FLJ32312;CCDC139;Coiled coil domain containing protein 139;DOBI;MGC126729;tRNA pseudouridine 55 synthase;tRNA uridine isomerase;psi55 synthase;tRNA-uridine isomerase;pseudouridine synthase 10;tRNA pseudouridylate synthase;coiled-coil domain containing 139;coiled-coil domain-containing protein 139
Recombinant Proteins
- Mouse
- Chicken
- Zebrafish
- Human
- Mammalian Cells
- HEK293
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PUS10-13726M | Recombinant Mouse PUS10 Protein | Mammalian Cells | Mouse | His |
|
|
| PUS10-4315C | Recombinant Chicken PUS10 | Mammalian Cells | Chicken | His |
|
|
| PUS10-6244Z | Recombinant Zebrafish PUS10 | Mammalian Cells | Zebrafish | His |
|
|
| PUS10-2661HCL | Recombinant Human PUS10 293 Cell Lysate | HEK293 | Human | Non |
|
|
| Pus10-5259M | Recombinant Mouse Pus10 Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
|
|
| PUS10-5584H | Recombinant Human PUS10 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
|
|
| PUS10-7304M | Recombinant Mouse PUS10 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
|
| PUS10-7304M-B | Recombinant Mouse PUS10 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
Involved Pathway
PUS10 involved in several pathways and played different roles in them. We selected most pathways PUS10 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PUS10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
PUS10 has several biochemical functions, for example, RNA binding,pseudouridine synthase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PUS10 itself. We selected most functions PUS10 had, and list some proteins which have the same functions with PUS10. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA binding | WDHD1,DUSP11,U2AF1L4,SRRM4,AKAP1,EIF4H,BXDC2,RBM14,PRDM14,RPL9 |
| pseudouridine synthase activity | TRUB2,RPUSD2,RPUSD4,PUS3,PUS7,RPUSD1,PUS1,DKC1,PUSL1,PUS7L |
Interacting Protein
PUS10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PUS10 here. Most of them are supplied by our site. Hope this information will be useful for your research of PUS10.
Resources
Related Services
Related Products
References
- Kamalampeta, R; Keffer-Wilkes, LC; et al. tRNA Binding, Positioning, and Modification by the Pseudouridine Synthase Pus10. JOURNAL OF MOLECULAR BIOLOGY 425:3863-3874(2013).
- Joardar, A; Jana, S; et al. Role of forefinger and thumb loops in production of Psi 54 and Psi 55 in tRNAs by archaeal Pus10. RNA-A PUBLICATION OF THE RNA SOCIETY 19:1279-1294(2013).
