PURG
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Official Full Name
purine-rich element binding protein G -
Overview
The exact function of this gene is not known, however, its encoded product is highly similar to purine-rich element binding protein A. The latter is a DNA-binding protein which binds preferentially to the single strand of the purine-rich element termed PUR, and has been implicated in the control of both DNA replication and transcription. This gene lies in close proximity to the Werner syndrome gene, but on the opposite strand, on chromosome 8p11. Two transcript variants encoding different isoforms have been found for this gene. -
Synonyms
PURG;purine-rich element binding protein G;purine-rich element-binding protein gamma;PURG A;PURG B;MGC119274;Pur gamma;Purine rich element binding protein G;Purine rich element binding protein gamma;Pur-gamma;PURG-A;PURG-B
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PURG-13724M | Recombinant Mouse PURG Protein | Mammalian Cell | Mouse | His |
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| PURG-31267TH | Recombinant Human PURG | Human | Non | Full L. |
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| PURG-2664HCL | Recombinant Human PURG 293 Cell Lysate | HEK293 | Human | Non |
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| PURG-7303M | Recombinant Mouse PURG Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| PURG-7303M-B | Recombinant Mouse PURG Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
PURG involved in several pathways and played different roles in them. We selected most pathways PURG participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PURG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
PURG has several biochemical functions, for example, DNA binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PURG itself. We selected most functions PURG had, and list some proteins which have the same functions with PURG. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | HERC5,HNRNPF,MRPL41,TCP1,SUMO1,RPL35,CANX,MRPL11,TRMT1L,ZC3H11A |
| DNA binding | ZHX1,TEAD2,ZNF285A,RYBPB,EGR2B,CARHSP1,GEN1,RNF11,TMEM18,TIGD3 |
Interacting Protein
PURG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PURG here. Most of them are supplied by our site. Hope this information will be useful for your research of PURG.
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References
- Sohail, M; Cao, WG; et al. Evolutionarily emerged G tracts between the polypyrimidine tract and 3 ' AG are splicing silencers enriched in genes involved in cancer. BMC GENOMICS 15:-(2014).
- Ramsey, JE; Kelm, RJ; et al. Mechanism of Strand-Specific Smooth Muscle alpha-Actin Enhancer Interaction by Purine-Rich Element Binding Protein B (Pur beta). BIOCHEMISTRY 48:6348-6360(2009).
