PTPRD
-
Official Full Name
protein tyrosine phosphatase, receptor type, D -
Overview
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5. -
Synonyms
PTPRD;protein tyrosine phosphatase, receptor type, D;receptor-type tyrosine-protein phosphatase delta;HPTP;PTPD;R-PTP-delta;protein-tyrosine phosphatase delta;protein tyrosine phosphatase, receptor type, delta polypeptide;HPTPD;HPTPDELTA;RPTPDELTA
Recombinant Proteins
- Human
- E.coli
- HEK293
- GST
- His
- Non
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PTPRD-2060H | Recombinant Human PTPRD, GST-tagged | E.coli | Human | GST | 541-829aa | |
| PTPRD-3740H | Recombinant Human PTPRD protein, His-tagged | E.coli | Human | His | 541-829 aa | |
| PTPRD-3759H | Recombinant Human PTPRD protein, His-tagged | E.coli | Human | His | 1089-1225 aa | |
| PTPRD-36H | Recombinant Human PTPRD protein, His-tagged | HEK293 | Human | His | 1245 |
|
| PTPRD-2678HCL | Recombinant Human PTPRD 293 Cell Lysate | HEK293 | Human | Non |
|
|
| PTPRD-2642H | Recombinant Human PTPRD Protein, His-tagged | E.coli | Human | His | Glu21-Ala219 |
|
| PTPRD-807H | Recombinant Full Length Human PTPRD Protein, Untagged | HEK293 | Human | Non | Full L. 1-1912 a.a. |
|
Involved Pathway
PTPRD involved in several pathways and played different roles in them. We selected most pathways PTPRD participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PTPRD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
PTPRD has several biochemical functions, for example, cell adhesion molecule binding,protein binding,receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PTPRD itself. We selected most functions PTPRD had, and list some proteins which have the same functions with PTPRD. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transmembrane receptor protein tyrosine phosphatase activity | PTPRA,PTPRF,PTPRM,PTPRS,PTPN6,EVLA,PTPRB,PTPRC,PTPRO,PTPRUB |
| receptor binding | SLC39A1,EHHADH,ADCYAP1,SMAGP,MAG,HRG,REN,LYN,NPY,PVRL3 |
| cell adhesion molecule binding | PVRL3,PVR,CADM1A,PVRL3B,ITGB1,POSTNB,NRXN1,GRIN2A,PVRL1A,CADM1B |
| protein binding | RAET1D,MED17,MAP2K3,KRT6B,PHC3,RAD1,NR2C2,ALKBH6,SMNDC1,COL18A1 |
Interacting Protein
PTPRD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTPRD here. Most of them are supplied by our site. Hope this information will be useful for your research of PTPRD.
STAT3;MDM2;EGFR
Resources
Related Services
Related Products
References
