PSTPIP1
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Official Full Name
proline-serine-threonine phosphatase interacting protein 1 -
Overview
The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome. -
Synonyms
PSTPIP1;proline-serine-threonine phosphatase interacting protein 1;proline-serine-threonine phosphatase-interacting protein 1;CD2 antigen binding protein 1;CD2 cytoplasmic tail binding protein;CD2BP1;CD2BP1L;CD2BP1S;H PIP;PAPAS;PEST phosphatase interacting protein 1;PSTPIP;CD2 binding protein 1;HPIP;Proline serine threonine phosphatase interacting protein 1;CD2-binding protein 1;CD2 antigen-binding protein 1;CD2 cytoplasmic tail-binding protein;PEST phosphatase-interacting protein 1;H-PIP
Recombinant Proteins
- Mouse
- Human
- Mammalian Cell
- E.coli
- HEK293
- HEK293T
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PSTPIP1-13616M | Recombinant Mouse PSTPIP1 Protein | Mammalian Cell | Mouse | His |
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| PSTPIP1-204H | Recombinant Human proline-serine-threonine phosphatase interacting protein 1, His-tagged | E.coli | Human | His | 1-416 a.a. |
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| PSTPIP1-2732HCL | Recombinant Human PSTPIP1 293 Cell Lysate | HEK293 | Human | Non |
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| PSTPIP1-1013H | Recombinant Human PSTPIP1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Pstpip1-5210M | Recombinant Mouse Pstpip1 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| PSTPIP1-7237M | Recombinant Mouse PSTPIP1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| PSTPIP1-7237M-B | Recombinant Mouse PSTPIP1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
PSTPIP1 involved in several pathways and played different roles in them. We selected most pathways PSTPIP1 participated on our site, such as NOD-like receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PSTPIP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| NOD-like receptor signaling pathway | RELA,NAIP7,MAPK8A,IL18,MAPK9,CXCL2,TAB2,HSP90AA1,BIRC2,NFKBIAA |
Protein Function
PSTPIP1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PSTPIP1 itself. We selected most functions PSTPIP1 had, and list some proteins which have the same functions with PSTPIP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | BMP4,LY96,SLC5A1,SLC6A3,CCDC70,PCNA,STX2,PTPN1,TWIST1,PIPOX |
Interacting Protein
PSTPIP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PSTPIP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PSTPIP1.
CD2;FASLG;PTPN12;UBE2W
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