PRSS12
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Official Full Name
protease, serine, 12 (neurotrypsin, motopsin) -
Overview
This gene encodes a member of the trypsin family of serine proteases. Studies in mouse suggest that the encoded enzyme may be involved in structural reorganizations associated with learning and memory. The enzyme is also expressed in Leydig cells in the testis, but its function in this tissue is unknown. Defects in this gene are a cause of mental retardation autosomal recessive type 1 (MRT1). -
Synonyms
PRSS12;protease, serine, 12 (neurotrypsin, motopsin);neurotrypsin;BSSP 3;MRT1;leydin;brain-specific serine protease 3;BSSP3;BSSP-3;MGC12722
Recombinant Proteins
- Mouse
- Rhesus macaque
- Rat
- Human
- Mammalian Cells
- E.coli
- HEK293
- His
- His&T7
- Non
- His&SUMO
- His&Fc&Avi
Involved Pathway
PRSS12 involved in several pathways and played different roles in them. We selected most pathways PRSS12 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PRSS12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
PRSS12 has several biochemical functions, for example, scavenger receptor activity,serine-type endopeptidase activity,serine-type peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PRSS12 itself. We selected most functions PRSS12 had, and list some proteins which have the same functions with PRSS12. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| serine-type endopeptidase activity | CTRC,LTF,GZMH,CTRL,PARLA,OVCH2,Acr,C1RA,KLK7,ST14B |
| serine-type peptidase activity | HTRA3,MCPT9,ZFYVE9,PRSS28,ELA2L,TPSAB1,PRSS59.1,ST14A,MCPT2,ELA3L |
| scavenger receptor activity | VTN,TMPRSS4A,LOXL2B,ENDOU,MARCO,TMPRSS2,SRCRB4D,LOXL4,SCARA3,LOXL3A |
Interacting Protein
PRSS12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRSS12 here. Most of them are supplied by our site. Hope this information will be useful for your research of PRSS12.
SH3PXD2A;PRPF40A;PPIL3;CNTLN
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References
- Henriques, A; Kastner, S; et al. Gene expression changes in spinal motoneurons of the SOD1(G93A) transgenic model for ALS after treatment with G-CSF. FRONTIERS IN CELLULAR NEUROSCIENCE 8:-(2015).
- Titheradge, H; Togneri, F; et al. Axenfeld-Rieger syndrome: Further clinical and array delineation of four unrelated patients with a 4q25 microdeletion. AMERICAN JOURNAL OF MEDICAL GENETICS PART A 164:1695-1701(2014).
