PROKR1
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Official Full Name
prokineticin receptor 1 -
Overview
Prokineticin receptor 1, also known as PKR1, is a human protein encoded by the PROKR1 gene. -
Synonyms
PROKR1;prokineticin receptor 1;G protein coupled receptor 73 , GPR73;GPR73a;PKR1;ZAQ;PK-R1;G protein-coupled receptor 73;G-protein coupled receptor 73;G protein-coupled receptor ZAQ;G-protein coupled receptor ZAQ;GPR73
Recombinant Proteins
- Human
- Mouse
- Rat
- Mus musculus
- Bovine
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- DDK
- Myc
- Avi
- Fc
- Flag
- Non
Involved Pathway
PROKR1 involved in several pathways and played different roles in them. We selected most pathways PROKR1 participated on our site, such as Class A/1 (Rhodopsin-like receptors),G alpha (q) signalling events,GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with PROKR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| G alpha (q) signalling events | LPAR1,RGS21,QRFP,NPSR1,LTB4R,GPRC6A,NPFFR2,CHRM3,NMBB,NMBA |
| Class A/1 (Rhodopsin-like receptors) | HCAR1-2,CHRM1,QRFPR,CNR1,CCR6,CCR9,OPN1SW,SSTR1,ADRB3,HRH3 |
| Signaling by GPCR | GPR132B,GPR37B,FGD4,GPR77,OPN4.1,CCL35.1,GPR31B,RGS7,CNR2,EMR3 |
| Signal Transduction | ARHGEF18A,FGFBP3,EMR2,PRICKLE1,FAM13B,ABCA4A,SKIB,DEPDC7,LINGO1,CSNK1G2 |
| GPCR ligand binding | TAAR1,GAL,GRP,GPR77,ACKR4,TRH,GPR4,SST,NTS,PTGDR2 |
| Peptide ligand-binding receptors | PENKA,PNOCB,QRFPR,SSTR5,AMCF-II,CCL35.2,HEBP1,XK,CCL35.1,PROKR2 |
| Gastrin-CREB signalling pathway via PKC and MAPK | TAC3,PROK1,PROKR1A,LTB4R,DGKG,MGLL,TRPC7,EDN1,RASGRP2,NMS |
| GPCR downstream signaling | HCRT,PTHRP2,RHOGA,PYY,DRD5,PROK1,KALRNB,SSTR1,RGS7,GPBAR1 |
Protein Function
PROKR1 has several biochemical functions, for example, G-protein coupled receptor activity,neuropeptide Y receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PROKR1 itself. We selected most functions PROKR1 had, and list some proteins which have the same functions with PROKR1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| G-protein coupled receptor activity | GPR141,RXFP3.2B,TAAR19P,TACR1A,MRGPRD,OR10C1,OR10A5,OXGR1A.2,OPRD1B,FZD3A |
| neuropeptide Y receptor activity | PRLHR,NPY8AR,NPY2R,PRLH2R,NPY1R,NPY5R,PROKR2,QRFPR,NPY8BR,PRLHR2B |
Interacting Protein
PROKR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PROKR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PROKR1.
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References
- Brouillet, S; Hoffmann, P; et al. Molecular Characterization of EG-VEGF-mediated Angiogenesis: Differential Effects on Microvascular and Macrovascular Endothelial Cells. MOLECULAR BIOLOGY OF THE CELL 21:2832-2843(2010).
