PRODH
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Official Full Name
proline dehydrogenase (oxidase) 1 -
Overview
This gene encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4). This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. -
Synonyms
PRODH;proline dehydrogenase (oxidase) 1;proline dehydrogenase (proline oxidase );proline dehydrogenase 1, mitochondrial;HSPOX2;PIG6;PRODH1;PRODH2;TP53I6;proline oxidase 2;p53-induced gene 6 protein;proline oxidase, mitochondrial;tumor protein
Recombinant Proteins
- Mouse
- Human
- Mammalian Cells
- Wheat Germ
- E.coli
- HEK293
- His
- Non
- T7
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PRODH-13428M | Recombinant Mouse PRODH Protein | Mammalian Cells | Mouse | His |
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| PRODH-31088TH | Recombinant Human PRODH | Wheat Germ | Human | Non | 100 amino acids |
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| PRODH-326H | Recombinant Full Length Human PRODH Protein, His-tagged | E.coli | Human | His | Full L. 1-600 a.a. |
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| Prodh-8048M | Recombinant Mouse Prodh protein, His & T7-tagged | E.coli | Mouse | His&T7 | Arg398~Gly551 |
|
| PRODH-502HCL | Recombinant Human PRODH lysate | HEK293 | Human | Non |
|
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| PRODH-7130M | Recombinant Mouse PRODH Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| PRODH-7130M-B | Recombinant Mouse PRODH Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
PRODH involved in several pathways and played different roles in them. We selected most pathways PRODH participated on our site, such as Arginine and proline metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRODH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Arginine and proline metabolism | NOS3,CKMT2B,ALDH1B1,GATM,ADC,DAO.1,ALDH3A2A,SMS,ALDH4A1,NOS2B |
| Metabolic pathways | ALG10B,LALBA,ADPGK,CYCS,HYAL3,GCSHB,ENO1B,TH,CYP2C18,POLR3B |
Protein Function
PRODH has several biochemical functions, for example, FAD binding,proline dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PRODH itself. We selected most functions PRODH had, and list some proteins which have the same functions with PRODH. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| proline dehydrogenase activity | PRODH2 |
| FAD binding | MTRR,DAO.3,KMO,MICAL1,DAO.2,DAO.1,DAO,CYB5R3,COQ6,MICAL2B |
Interacting Protein
PRODH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRODH here. Most of them are supplied by our site. Hope this information will be useful for your research of PRODH.
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