Prex2

  • Official Full Name

    phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2

    Involved Pathway

    Prex2 involved in several pathways and played different roles in them. We selected most pathways Prex2 participated on our site, such as Regulation of RAC1 activity, which may be useful for your reference. Also, other proteins which involved in the same pathway with Prex2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Regulation of RAC1 activity ARHGAP9,ABR,DEF6,ARHGAP1,CHN1,DOCK6,ARHGEF25,RAP1GDS1,RALBP1,CHN2

    Protein Function

    Prex2 has several biochemical functions, for example, GTPase activator activity,Rac guanyl-nucleotide exchange factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Prex2 itself. We selected most functions Prex2 had, and list some proteins which have the same functions with Prex2. You can find most of the proteins on our site.

    Function Related Protein
    Rac guanyl-nucleotide exchange factor activity ARHGEF4,VAV3,SPATA13,ARHGEF2,FARP2,FARP1,ALS2,VAV1,DOCK2
    GTPase activator activity RASAL2,GDI1,RIC8A,RGS11,ASAP3,MURC,LRRK2,ARHGAP17,GRTP1,SRGAP2B

    Interacting Protein

    Prex2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Prex2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Prex2.

    PPP1CA;SMAD2;MYC

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