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PPL

Official Full Name

Periplakin
Overview

Periplakin, or PPL, is a component of the cornified envelope of keratinocytes. It may link the cornified envelope to desmosomes and intermediate filaments and act as a localization signal in PKB/AKT-mediated signaling.
Synonyms

PPL; periplakin; 190 kDa paraneoplastic pemphigus antigen; 195 kDa cornified envelope precursor protein; KIAA0568; MGC134872; OTTHUMP00000159922;

Type

Recombinant Proteins
Chromatography Reagents

Species

Human
Mouse
Zebrafish

Source

E.coli
Mammalian Cell

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PPL-727H	Recombinant Human PPL Protein, His/GST-tagged	E.coli	His&GST	Glu1439~Gly1716	$298 / 10μg
Human	PPL-3166H	Recombinant Human PPL Protein (Glu1439-Gly1716), His tagged	E.coli	His	Glu1439-Gly1716	Inquiry
Human	PPL-726H	Recombinant Human PPL Protein, His-tagged	E.coli	His	Glu1439~Gly1716	$298 / 10μg
Human	PPL-2472H	Recombinant Human PPL protein(691-1260 aa), C-His-tagged	E.coli	His	691-1260 aa	Inquiry
Mouse	Ppl-728M	Recombinant Mouse Ppl Protein, His-tagged	E.coli	His	Glu1501~Lys1754	$298 / 10μg
Zebrafish	PPL-7224Z	Recombinant Zebrafish PPL	Mammalian Cell	His		Inquiry
	COP25	Protein L Agarose High Flow Resin		Non		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

PPL involved in several pathways and played different roles in them. We selected most pathways PPL participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PPL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

PPL has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by PPL itself. We selected most functions PPL had, and list some proteins which have the same functions with PPL. You can find most of the proteins on our site.

Function	Related Protein
molecular_function	ZZEF1;MS4A6B;DENND2DB;FAM149B;SAMM50L;TMEM151B;HSPA7;MXRA8;INPP4AA

PPL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPL here. Most of them are supplied by our site. Hope this information will be useful for your research of PPL.

Research Area

He, T; Ding, YY; et al. In vitro molecular evolution of AL NEIBMs improved immunoglobulin (Ig) binding and antibody detection. JOURNAL OF BIOTECHNOLOGY 184:118-127(2014).

Patil, R; Ghosh, K; et al. Elevated Procoagulant Endothelial and Tissue Factor Expressing Microparticles in Women with Recurrent Pregnancy Loss. PLOS ONE 8:-(2013).