POU4F2
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Official Full Name
POU class 4 homeobox 2 -
Overview
The protein encoded by this gene is a member of the POU-domain transcription factor family and may be involved in maintaining visual system neurons in the retina. The level of the encoded protein is also elevated in a majority of breast cancers, resulting in accelerated tumor growth. -
Synonyms
POU4F2;POU class 4 homeobox 2;BRN3B, POU domain class 4, transcription factor 2 , POU domain, class 4, transcription factor 2;POU domain, class 4, transcription factor 2;Brn 3b;BRN3B;Brain-specific homeobox/POU domain protein 3B;Brn-3B;POU domain class 4 transcription factor 2;brain-3B;OTTHUMP00000221146;POU domain protein;Brn3b POU domain transcription factor;BRN3.2
Recombinant Proteins
- Zebrafish
- Mouse
- Human
- Mammalian Cells
- HEK293
- E.coli
- His
- Myc&DDK
- His&Myc
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| POU4F2-12073Z | Recombinant Zebrafish POU4F2 | Mammalian Cells | Zebrafish | His |
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| POU4F2-13146M | Recombinant Mouse POU4F2 Protein | Mammalian Cells | Mouse | His |
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| POU4F2-2604H | Recombinant Human POU4F2 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| POU4F2-2672H | Recombinant Human POU4F2 Protein (1-265 aa), His-Myc-tagged | E.coli | Human | His&Myc | 1-265 aa |
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| POU4F2-409H | Recombinant Human POU4F2 Protein, MYC/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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| Pou4f2-5023M | Recombinant Mouse Pou4f2 Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| POU4F2-6956M | Recombinant Mouse POU4F2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| POU4F2-6956M-B | Recombinant Mouse POU4F2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
POU4F2 involved in several pathways and played different roles in them. We selected most pathways POU4F2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with POU4F2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
POU4F2 has several biochemical functions, for example, DNA binding,RNA polymerase II core promoter proximal region sequence-specific DNA binding,chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by POU4F2 itself. We selected most functions POU4F2 had, and list some proteins which have the same functions with POU4F2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription factor activity, sequence-specific DNA binding | INSM1B,RXRGA,POU2F2,PHOX2A,SPI1,FBXW7,ATF7A,RUNX2,ZNF500,ZFP184 |
| DNA binding | PAX8,ZFP488,REV3L,SP1,SFPI1,POU3F3A,RAD51L3,LHX6,RBM5,ZFP541 |
| sequence-specific DNA binding | HOXB3A,RORCA,PKNOX1.1,HOXD12A,FOXD1L,GSC,HSFY1,HIVEP2A,POUV,DBX1B |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | FOSL1,HAND1,NR6A1,ZNF543,OVOL1,FOXJ1,FOXL2,CTCFL,RFX1,PDX1 |
| chromatin binding | PHF21A,HMGB1A,PBRM1L,MSGN1,TRPS1,POLG,WDR82,CHAF1A,HMGB3,POLA1 |
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | ISL1,HOXC13,RFX4,ALS2CR8,FIGLA,SMAD4,ARNT2,SOX4,MITF,NFIA |
| transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding | PRDM5,ZKSCAN3,ZNF217,OVOL1,E2F8,GZF1,TFAP2A,TGIF1,ASCL1,HHEX |
Interacting Protein
POU4F2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POU4F2 here. Most of them are supplied by our site. Hope this information will be useful for your research of POU4F2.
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