POU4F1
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Official Full Name
POU class 4 homeobox 1 -
Overview
This gene encodes a member of the POU-IV class of neural transcription factors. This protein is expressed in a subset;of retinal ganglion cells and may be involved in the developing sensory nervous system. This protein may also promote;the growth of cervical tumors. A translocation of this gene is associated with some adult acute myeloid leukemias.
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| POU4F1-11434Z | Recombinant Zebrafish POU4F1 | Mammalian Cells | Zebrafish | His |
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| POU4F1-13145M | Recombinant Mouse POU4F1 Protein | Mammalian Cells | Mouse | His |
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| POU4F1-2605H | Recombinant Human POU4F1 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| Pou4f1-5022M | Recombinant Mouse Pou4f1 Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| POU4F1-6955M | Recombinant Mouse POU4F1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| POU4F1-6955M-B | Recombinant Mouse POU4F1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
POU4F1 involved in several pathways and played different roles in them. We selected most pathways POU4F1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with POU4F1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
POU4F1 has several biochemical functions, for example, DNA binding,RNA polymerase II distal enhancer sequence-specific DNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by POU4F1 itself. We selected most functions POU4F1 had, and list some proteins which have the same functions with POU4F1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | NKX2-8,FOXI1,TFAP2A,MYC,PITX1,LEF1,NEUROG3,MEF2C,PLAG1,SIX2 |
| DNA binding | ZNF354A,SETDB2,H2AFY,NUSAP1,ACD,ZNF593,ZNF653,IRF7,POLR3B,HIST1H110 |
| sequence-specific DNA binding | THRAA,EGR1,FOXJ1B,ZFP191,RORC,TFAP4,DBPB,LHX2A,POU3F1,PAX7B |
| protein binding | GADD45GIP1,YWHAZ,KRTAP9-4,HNRNPH1,SV2B,BOK,CEP85,CEBPA,RPL39L,FUT11 |
| transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding | ARID3B,SUB1,BACH1,CUX1,HOXB5,REL,SPI1,NFKB1,HCFC1,PROP1 |
| RNA polymerase II distal enhancer sequence-specific DNA binding | NR2F6,ARX,CDX1,GATA2,NR1H4,H3F3A,MED12,PBX3,NR5A1,PAX4 |
| transcription factor activity, sequence-specific DNA binding | ZFP629,EGR2,DMRTC1B,NFE2L1A,PA2G4,MNX2A,FOXP2,ATF7A,RORC,HOXB8B |
| transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | RFX3,NFATC1,MEF2C,POU3F1,TEAD2,AHR,JUN,LEF1,TFAP4,SOX7 |
Interacting Protein
POU4F1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POU4F1 here. Most of them are supplied by our site. Hope this information will be useful for your research of POU4F1.
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