POU3F2

  • Official Full Name

    POU class 3 homeobox 2

  • Overview

    This gene encodes a member of the POU-III class of neural transcription factors. The encoded protein is involved in;neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes.;Overexpression of this protein is associated with an increase in the proliferation of melanoma cells.

  • Synonyms

    POU3F2;POU class 3 homeobox 2;OTF7, POU domain class 3, transcription factor 2;POU domain, class 3, transcription factor 2;BRN2;OCT7;POUF3;brain-2;octamer-binding protein 7;octamer-binding transcription factor 7;brain-specific homeobox/POU doma

Recombinant Proteins

  • Human
  • Mouse
  • Rat
  • E.coli
  • Mammalian Cell
  • HEK293T
  • HEK293
  • Mammalian cells
  • GST
  • His
  • Arg
  • Myc&DDK
  • His&Fc&Avi
  • Flag

    Involved Pathway

    POU3F2 involved in several pathways and played different roles in them. We selected most pathways POU3F2 participated on our site, such as SIDS Susceptibility Pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with POU3F2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    SIDS Susceptibility Pathways CTCF,RUNX3,KCNQ1,CHRFAM7A,YBX1,SNTA1,ASCL1,CDCA7L,DLX2,EN1

    Protein Function

    POU3F2 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding,RNA polymerase II transcription coactivator activity,identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by POU3F2 itself. We selected most functions POU3F2 had, and list some proteins which have the same functions with POU3F2. You can find most of the proteins on our site.

    Function Related Protein
    protein binding CRELD2,NME5,TRIM71,HSPB8,PPP2R5D,SRPK1,CXCR7,RAB7A,LEF1,ZFP143
    transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding GLI2,ALS2CR8,NEUROD6,MITF,NEUROG3,CTCFL,HOXA10,ESR1,ZSCAN21,ZNF750
    identical protein binding LYZ,ERN1,LCK,PCM1,GPSM2,NOL3,WAS,PLEKHH2,PYDC3,GNPNAT1
    RNA polymerase II core promoter proximal region sequence-specific DNA binding CREB3,ZNF718,SOX10,YBX1,SRF,AKNA,NDN,TFAP2A,CREB3L2,HIST2H3A
    transcription factor activity, sequence-specific DNA binding TBPL2,ZSCAN4C,RARAA,DMRTC1C2,RBPJA,NKX6-2,DLX2,RARGA,GATA2B,SIN3A
    RNA polymerase II transcription coactivator activity POU1F1,MKL1B,TBX20,ANKRD1,CITED2,POU3F1,CITED4,PHF17,PITX2,PRRX1

    Interacting Protein

    POU3F2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POU3F2 here. Most of them are supplied by our site. Hope this information will be useful for your research of POU3F2.

    EP300;TBP;PAX3;SOX10;GTF2B;q9wmx2-pro_0000037547

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