POLQ
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Official Full Name
polymerase (DNA directed), theta -
Overview
DNA polymerase theta is an enzyme that in humans is encoded by the POLQ gene. -
Synonyms
POLQ;polymerase (DNA directed), theta;DNA polymerase theta;POLH;DNA polymerase eta;PRO0327;DKFZp781A0112
Recombinant Proteins
- Human
- E.coli
- Wheat Germ
- Insect cells
- His&Myc
- GST
- N-His-SUMO
- His
- N-His&C-Flag
- N-His&C-Myc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| POLQ-1189H | Recombinant Human POLQ protein, His&Myc-tagged | E.coli | Human | His&Myc | 321-554aa |
|
| POLQ-23H | Recombinant Human POLQ Protein, GST-tagged | Wheat Germ | Human | GST | 2572-2680 a.a. |
|
| POLQ-27H | Recombinant Human POLQ Protein (C terminal Domain, 1792-2590) | E.coli | Human | 1792-2590 |
|
|
| POLQ-322H | Recombinant Human POLQ protein, His-SUMO-tagged | E.coli | Human | N-His-SUMO | 1820-2590aa |
|
| POLQ-3522H | Recombinant Human POLQ protein, His-tagged | Insect cells | Human | His | 1792-2590aa |
|
| POLQ-4543H | Recombinant Human POLQ protein, His-tagged | E.coli | Human | His | 1820-2590aa |
|
| POLQ-4544H | Recombinant Human POLQ protein, His&Flag-tagged | Insect cells | Human | N-His&C-Flag | 1820-2590aa |
|
| POLQ-654H | Recombinant Human POLQ protein, His&Flag-tagged | Insect cells | Human | N-His&C-Flag | 1-987aa |
|
| POLQ-7643H | Recombinant Human POLQ protein, His&Myc-tagged | E.coli | Human | N-His&C-Myc | 1792-2590aa |
|
Involved Pathway
POLQ involved in several pathways and played different roles in them. We selected most pathways POLQ participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with POLQ were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
POLQ has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by POLQ itself. We selected most functions POLQ had, and list some proteins which have the same functions with POLQ. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
POLQ has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POLQ here. Most of them are supplied by our site. Hope this information will be useful for your research of POLQ.
Resources
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References
- Yousefzadeh, MJ; Wyatt, DW; et al. Mechanism of Suppression of Chromosomal Instability by DNA Polymerase POLQ. PLOS GENETICS 10:-(2014).
- Kohzaki, M; Nishihara, K; et al. DNA polymerases nu and theta are required for efficient immunoglobulin V gene diversification in chicken. JOURNAL OF CELL BIOLOGY 189:1117-1127(2010).
