PLUNC
-
Official Full Name
palate, lung and nasal epithelium associated -
Overview
This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The exact biological function of this gene is not known, however, it has been suggested to be involved in inflammatory responses to irritants in the upper airways. It may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3" UTR have been detected, but the full-length nature of only two is known. -
Synonyms
palate, lung and nasal epithelium associated;Von Ebner protein Hl;LUNX;NASG;SPURT;bA49G10.5;palate, lung and nasal epithelium carcinoma associated;Lung-specific protein X;Nasopharyngeal carcinoma-related protein;ligand-binding protein RYA3;Palate lung and nasal epithelium clone protein;Secretory protein in upper respiratory tracts;tracheal epithelium enriched protein;Tracheal epithelium-enriched protein;LPLUNC3;SPLUNC1;protein Plunc;OTTHUMP00000030625;OTTHUMP00000030626;OTTHUMP00000030627;PLUNC;palate, lung and nasal epithelium associated
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PLUNC-3092HCL | Recombinant Human PLUNC 293 Cell Lysate | HEK293 | Human | Non |
|
|
| PLUNC-3093HCL | Recombinant Human PLUNC 293 Cell Lysate | HEK293 | Human | Non |
|
Involved Pathway
PLUNC involved in several pathways and played different roles in them. We selected most pathways PLUNC participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PLUNC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
PLUNC has several biochemical functions, for example, lipid binding,molecular_function,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PLUNC itself. We selected most functions PLUNC had, and list some proteins which have the same functions with PLUNC. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | TNIP3,AIG1,KIF6,SMAD9,HIST1H4A,SPPL2B,LCE3C,COPE,LRCH3,HOMEZ |
| molecular_function | MRGPRA7,DEFB34,HYDIN,GID8A,KCTD3,ZNF664,DEFB41,ADPRM,GM8898,Mamdc4 |
| lipid binding | SNX10A,STARD10,SH3GL3,APOA4B.2,FFAR1,APOA4,FAM123A,PTGS2,BPIFB2,MELK |
Interacting Protein
PLUNC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLUNC here. Most of them are supplied by our site. Hope this information will be useful for your research of PLUNC.
UBQLN1;Ikbip;UBQLN4
Resources
Related Services
Related Products
References
- Musa, M; Wilson, K; et al. Differential localisation of BPIFA1 (SPLUNC1) and BPIFB1 (LPLUNC1) in the nasal and oral cavities of mice. CELL AND TISSUE RESEARCH 350:455-464(2012).
- Balakrishnan, A; Marathe, SA; et al. Bactericidal/permeability increasing protein: A multifaceted protein with functions beyond LPS neutralization. INNATE IMMUNITY 19:339-347(2013).
