PLEKHB1

  • Official Full Name

    pleckstrin homology domain containing, family B (evectins) member 1

  • Overview

    This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.

  • Synonyms

    PLEKHB1;pleckstrin homology domain containing, family B (evectins) member 1;KPL1;PHR1;PHRET1

Recombinant Proteins

  • Human
  • Mouse
  • Chicken
  • Rat
  • E.coli
  • Mammalian Cell
  • HEK293
  • HEK293T
  • GST
  • His
  • Non
  • Myc&DDK
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
PLEKHB1-1780H Recombinant Human PLEKHB1, GST-tagged E.coli Human GST 17-189
PLEKHB1-12949M Recombinant Mouse PLEKHB1 Protein Mammalian Cell Mouse His
PLEKHB1-1920C Recombinant Chicken PLEKHB1 Mammalian Cell Chicken His
PLEKHB1-4515R Recombinant Rat PLEKHB1 Protein Mammalian Cell Rat His
PLEKHB1-485HCL Recombinant Human PLEKHB1 lysate HEK293 Human Non
PLEKHB1-2105H Recombinant Human PLEKHB1 Protein, MYC/DDK-tagged HEK293 Human Myc&DDK
PLEKHB1-4175R Recombinant Rat PLEKHB1 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
PLEKHB1-4175R-B Recombinant Rat PLEKHB1 Protein Pre-coupled Magnetic Beads HEK293 Rat
Plekhb1-4927M Recombinant Mouse Plekhb1 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
PLEKHB1-6831M Recombinant Mouse PLEKHB1 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
PLEKHB1-6831M-B Recombinant Mouse PLEKHB1 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    PLEKHB1 involved in several pathways and played different roles in them. We selected most pathways PLEKHB1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PLEKHB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    PLEKHB1 has several biochemical functions, for example, protein C-terminus binding,protein binding,protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PLEKHB1 itself. We selected most functions PLEKHB1 had, and list some proteins which have the same functions with PLEKHB1. You can find most of the proteins on our site.

    Function Related Protein
    protein homodimerization activity ERBB3,IZUMO1,SLC26A5,P2RX4,S100A13,GSTA4,NR4A3,P2RX7,DARS2,PYGB
    protein C-terminus binding CSK,HESX1,ZBTB16,ERCC1,NEFL,PROP1,HSPG2,SDCBP2,PEX12,SIAH1
    signal transducer activity VAPA,TAAR11,TAAR13D,PTGER1A,TAS2R202,TAAR13B,GPR62,OLFR154,GOLT1B,STMN1
    protein binding NPBWR2,PIAS3,CBX6,MED16,KRTAP13-3,CLK4,FBXO46,TMEM106C,PCGF6,CDC42EP4

    Interacting Protein

    PLEKHB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLEKHB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PLEKHB1.

    RAP1GDS1;ATXN1

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