Pld6
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Official Full Name
phospholipase D family, member 6
Recombinant Proteins
- Mouse
- Human
- Zebrafish
- Xenopus laevis
- Bovine
- zebrafish
- Dog
- Mammalian Cells
- E.coli
- HEK293
- His
- SUMO
- Avi
- Fc
- Non
Involved Pathway
Pld6 involved in several pathways and played different roles in them. We selected most pathways Pld6 participated on our site, such as Gene Expression,Gene Silencing by RNA,Glycerophospholipid biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with Pld6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Gene Expression | MED31,EIF2S3,TSEN2,ZNF37A,AIMP1,NT5C3B,LAGE3,NR1D2B,MTA1,NR1H3 |
| Metabolism | SLC5A6A,COX4I1,CHKB,CYP2AD6,CYP4F22,ZDHHC21,NUDT4B,UPP2,SLC25A1,SLC2A3 |
| PIWI-interacting RNA (piRNA) biogenesis | ASZ1,TDRD1,MAEL,HENMT1,DDX4,FKBP6,PIWIL4,MYBL1 |
| Gene Silencing by RNA | TSNAX,DPY19L2,DDX4,EIF2C3,ASZ1,FKBP6,DGCR8,HENMT1,TDRD1,TNRC6B |
| Metabolism of lipids and lipoproteins | FABP11B,PPM1LB,ABHD4,ARSD,CYP2Y3,MED25,GRHL1,APOA4B.2,GGTLC1,CPNE6 |
| Synthesis of PG | PTPMT1 |
| Glycerophospholipid biosynthesis | CHKA,PLD4,MGLL,CDIPT,PTPMT1,CPNE3,CPNE6,CHAT,AWAT2,CDS1 |
| Phospholipid metabolism | SLC44A5B,CHKB,PNPLA8,SACM1LA,PHOSPHO1,SACM1LB,DGAT1B,FIG4,CEPT1,CPNE7 |
Protein Function
Pld6 has several biochemical functions, for example, cardiolipin hydrolase activity,cardiolipin synthase activity,endoribonuclease activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Pld6 itself. We selected most functions Pld6 had, and list some proteins which have the same functions with Pld6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | ZFP629,ZNF80,ZNF483,CACNA1H,PRIM2,GALNT6,ZFP526,GALNT18A,GMPR2,INPP5B |
| endoribonuclease activity | AGO2,NOB1,RNASEL,CPSF3,DICER1,ENDOU,TSN,SMG6,RNASEKA,TSNAX |
| cardiolipin synthase activity | CRLS1 |
| protein homodimerization activity | PVRL1,CADM1,VPS4B,GRHPR,IRAK1,PAH,SFTPC,CADM2A,IDH1,S100A5 |
Interacting Protein
Pld6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Pld6 here. Most of them are supplied by our site. Hope this information will be useful for your research of Pld6.
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References
- Zhou, Q; Guo, YS; et al. Establishment of a proteome profile and identification of molecular markers for mouse spermatogonial stem cells. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 19:521-534(2015).
- Voigt, F; Reuter, M; et al. Crystal structure of the primary piRNA biogenesis factor Zucchini reveals similarity to the bacterial PLD endonuclease Nuc. RNA-A PUBLICATION OF THE RNA SOCIETY 18:2128-2134(2012).
