PIWIL4

  • Official Full Name

    piwi-like 4

  • Overview

    PIWIL4 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem;cells (Sasaki et al., 2003 (PubMed 12906857)).

  • Synonyms

    PIWIL4;piwi-like 4 (Drosophila);piwi-like protein 4;FLJ36156;HIWI2;Miwi2;DKFZp686P01248

Recombinant Proteins

  • Mouse
  • Rhesus macaque
  • Human
  • Mammalian Cell
  • HEK293
  • Mammalian cells
  • HEK293T
  • Yeast
  • His
  • Non
  • Flag
  • His&Fc&Avi
  • Myc&DDK

    Involved Pathway

    PIWIL4 involved in several pathways and played different roles in them. We selected most pathways PIWIL4 participated on our site, such as Dorso-ventral axis formation,Gene Expression,Gene Silencing by RNA, which may be useful for your reference. Also, other proteins which involved in the same pathway with PIWIL4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    PIWI-interacting RNA (piRNA) biogenesis MAEL,TDRD1,DDX4,FKBP6,PLD6,ASZ1,MYBL1,HENMT1
    Gene Silencing by RNA IPO8,TDRD1,FKBP6,DDX4,TNRC6B,DPY19L2,TSNAX,BARHL1,EIF2C3,MAEL
    Dorso-ventral axis formation GRB2B,SPIRE2,MAPK1,PPP1R2P9,MAP2K1,NOTCH1,EGFRA,CPEB4,KRAS,CPEB3
    Gene Expression DARS,HUG,DDX6,SAP30L,SNUPN,ZNF383,MBD3A,EIF2S1,ZNF558,ZNF691

    Protein Function

    PIWIL4 has several biochemical functions, for example, piRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PIWIL4 itself. We selected most functions PIWIL4 had, and list some proteins which have the same functions with PIWIL4. You can find most of the proteins on our site.

    Function Related Protein
    piRNA binding PIWIL2,PIWIL1

    Interacting Protein

    PIWIL4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PIWIL4 here. Most of them are supplied by our site. Hope this information will be useful for your research of PIWIL4.

    b4dyc6_human;FKBP6;HSP90AA1;FKBP5;PTGES3;HSP90AB1;NUDCD3;q96be0_human;PPP5C;AARSD1;CACYBP;AGO2;NUDC;DICER1

    Resources

    Research Area

    Germ Cell Markers

    References

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    Q&As

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