PIP5KL1
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Official Full Name
phosphatidylinositol-4-phosphate 5-kinase-like 1 -
Overview
PIP5KL1 is a phosphoinositide kinase-like protein that lacks intrinsic lipid kinase activity but associates with type I;PIPKs (see PIP5K1A; MIM 603275) and may play a role in localization of PIPK activity (Chang et al., 2004 (PubMed;14701839)). -
Synonyms
PIP5KL1;phosphatidylinositol-4-phosphate 5-kinase-like 1;phosphatidylinositol-4-phosphate 5-kinase-like protein 1;bA203J24.5;MGC46424;EC 2.7.1.68;phosphatidylinositol 4 phosphate 5 kinase like 1;phosphatidylinositol phosphate kinase homolog;PI(4)P 5 kinase like protein 1;PIPKH;PtdIns(4)P 5 kinase like protein 1;PI(4)P 5-kinase-like protein 1;ptdIns(4)P-5-kinase-like protein 1;RP11-203J24.5
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PIP5KL1-5675HF |
Active Recombinant Full Length Human PIP5KL1 Protein, GST-tagged
|
Insect (sf21) | Human | GST | Full L. 1-394(end) |
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| PIP5KL1-12831M | Recombinant Mouse PIP5KL1 Protein | Mammalian Cell | Mouse | His |
|
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| PIP5KL1-3171HCL | Recombinant Human PIP5KL1 293 Cell Lysate | HEK293 | Human | Non |
|
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| PIP5KL1-6758M | Recombinant Mouse PIP5KL1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
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| PIP5KL1-6758M-B | Recombinant Mouse PIP5KL1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
PIP5KL1 involved in several pathways and played different roles in them. We selected most pathways PIP5KL1 participated on our site, such as 3-phosphoinositide biosynthesis,D-myo-inositol (1,4,5)-trisphosphate biosynthesis,Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with PIP5KL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| 3-phosphoinositide biosynthesis | PIK3R6,CDIPT,FIG4 |
| Regulation of Actin Cytoskeleton | ITGA6B,PIKFYVE,MYH9,FGF5,MYL7,MAP2K2B,PDGFC,VAV2,FGF9,RAC1 |
| Metabolic pathways | CYP1A,GALT,TYRP1,GALNT4,CYCS,GALNT13,HPGDS,NOS3,UPB1,GFPT1 |
| Inositol phosphate metabolism | PTEN,PIP5K2,INPP4B,NUDT3A,PIK3C2G,MTMR6,NUDT11,PIKFYVE,TPI1A,INPP5J |
| D-myo-inositol (1,4,5)-trisphosphate biosynthesis | CDIPT,PLCD3 |
| Endocytosis | ARF6B,RAB11B,H2-Q10,SNX12,SMAP1,ERBB3,SH3GL2,HRASB,TRAF6,DNAJC6 |
| superpathway of inositol phosphate compounds | IP6K3 |
Protein Function
PIP5KL1 has several biochemical functions, for example, 1-phosphatidylinositol-4-phosphate 5-kinase activity,ATP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PIP5KL1 itself. We selected most functions PIP5KL1 had, and list some proteins which have the same functions with PIP5KL1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | DYRK2,EPHA5,MOV10,MYO1C,MCM9,ACTC1B,CAMKK1B,HSPA12B,NAIP6,ATAD1B |
| 1-phosphatidylinositol-4-phosphate 5-kinase activity | PIKFYVE,PIP4K2B,PIP5K1C,PIP5K1B,PIP4K2C,PIP4K2A,PIP5K1A |
Interacting Protein
PIP5KL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PIP5KL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PIP5KL1.
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