PIK3AP1
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Official Full Name
phosphoinositide-3-kinase adaptor protein 1
Recombinant Proteins
- Mouse
- Rhesus macaque
- Chicken
- Human
- Rat
- Mammalian Cell
- HEK293
- E. coli
- E.coli
- Mammalian cells
- HEK293T
- His
- Non
- His&Fc&Avi
- His&T7
- Flag
- Myc&DDK
Involved Pathway
PIK3AP1 involved in several pathways and played different roles in them. We selected most pathways PIK3AP1 participated on our site, such as Adaptive Immune System,Antigen activates B Cell Receptor (BCR) leading to generation of second messengers,B Cell Receptor Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PIK3AP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Adaptive Immune System | HUWE1,CD300LG,Siglece,TRAF7,FBXO3,FGF20A,TRIM50,KIF4,ASB11,CTSB |
| Immune System | EIF4E3,KLRB1A,GBP2,ABI1B,LILRB5,PANX1,TRIM69,CD300C,ASB6,CD200R2 |
| PI3K-Akt signaling pathway | PRP2,CDC37,CSF1,CSF3R,LAMC3,CSF1R,COMP,EFNA4,CSH1,CHAD |
| Signaling by the B Cell Receptor (BCR) | SRMS,IGHM,STIM1B |
| B Cell Receptor Signaling Pathway | FCGR2B,ACTR3,CDK2,PIK3R5,PPP3CA,RASGRP3,PPP3R2,RAC3,VAV2,IKBKG |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | STIM1B,SRMS,IGKV1-5,BLK,IGLC2,AHCYL1,IGKC,ITPR2,IGHM,AKR1C1 |
Protein Function
PIK3AP1 has several biochemical functions, for example, identical protein binding,phosphatidylinositol 3-kinase regulatory subunit binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PIK3AP1 itself. We selected most functions PIK3AP1 had, and list some proteins which have the same functions with PIK3AP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| identical protein binding | EPOR,IAPP,VPS4B,SOD2,P2RX2,SSNA1,MMP9,VAMP2,COL2A1,PRKD1 |
| phosphatidylinositol 3-kinase regulatory subunit binding | FAM83A,FAM83B,PIK3R1,XBP1,DNM2,PTPN13 |
Interacting Protein
PIK3AP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PIK3AP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PIK3AP1.
GRB2;Dlg4;ITSN1;clpB;q81x81_bacan
Resources
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References
- Shih, CH; Chiang, TB; et al. critical role for the regulation of Syk from agglutination to aggregation in human platelets. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 443:580-585(2014).
- Kim, EJ; Suk, K; et al. SHPS-1 and a synthetic peptide representing its ITIM inhibit the MyD88, but not TRIF, pathway of TLR signaling through activation of SHP and PI3K in THP-1 cells. INFLAMMATION RESEARCH 62:377-386(2013).
