PHLDA3
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Official Full Name
pleckstrin homology-like domain, family A, member 3 -
Overview
Pleckstrin homology-like domain family A member 3 (PHLDA3) is one of three relatively small, similar proteins that share a common pleckstrin homology (PH) domain. Expression of PHLDA3 and the related PHLDA1 occurs in several fetal and adult tissues, in co -
Synonyms
PHLDA3;pleckstrin homology-like domain, family A, member 3;pleckstrin homology-like domain family A member 3;pleckstrin homology like domain;family A;member 2;TIH1;TDAG51/Ipl homolog 1;pleckstrin homology-like domain, family A, member 2
Recombinant Proteins
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- Mammalian Cell
- HEK293
- Wheat Germ
- HEK293T
- In Vitro Cell Free System
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
PHLDA3 involved in several pathways and played different roles in them. We selected most pathways PHLDA3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PHLDA3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
PHLDA3 has several biochemical functions, for example, phosphatidylinositol-3,4,5-trisphosphate binding,phosphatidylinositol-3,4-bisphosphate binding,phosphatidylinositol-3,5-bisphosphate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PHLDA3 itself. We selected most functions PHLDA3 had, and list some proteins which have the same functions with PHLDA3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| phosphatidylinositol-3,4-bisphosphate binding | PLEK,D6WSU116E,ARAP3,ADAP2,COMMD1,DAPP1,ZFYVE1,ANXA8,AKT1,FAM21C |
| phosphatidylinositol-5-phosphate binding | SH3PXD2B,RS1,FAM21C,D6WSU116E,SNX3,JPH2,PLEKHF1,SESTD1,LANCL2,WIPI2 |
| phosphatidylinositol-3-phosphate binding | SNX24,BBS5,RS1,WDR45B,WDR45L,SESTD1,PLEKHF1,VPS36,WDR45,TECPR1 |
| phosphatidylinositol-4,5-bisphosphate binding | SNX18,MAPKAP1,SLC9A1,ADAP2,SYTL2,RAB35,KCNQ1,SESTD1,ANXA8,RAG2 |
| phosphatidylinositol-3,5-bisphosphate binding | SNX3,SH3PXD2B,RS1,SNX14,RAG2,MAPKAP1,WIPI1,FAM21C,D6WSU116E,CLVS2 |
| phosphatidylinositol-3,4,5-trisphosphate binding | PIRT,MYO1G,AKT1,FERMT2,BTK,FAM21C,CYTH3,ADAP2,COMMD1,RACGAP1 |
Interacting Protein
PHLDA3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PHLDA3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PHLDA3.
MYO1C;RFXANK;POLR1C;ZW10;IDH3B;DPM1;DNAJB6;SLC25A12;TRIO;ATP5L;MYO1D;UFL1;PRPF6;AHSA1;NTRK1;RPN2
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References
- Honarpisheh, H; Glusac, EJ; et al. Cytokeratin 20 expression in basaloid follicular hamartoma and infundibulocystic basal cell carcinoma. JOURNAL OF CUTANEOUS PATHOLOGY 41:916-921(2014).
