PHKG1
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Official Full Name
phosphorylase kinase, gamma 1 (muscle) -
Overview
This gene is a member of the Ser/Thr protein kinase family and encodes a protein with one protein kinase domain and two calmodulin-binding domains. This protein is the catalytic member of a 16 subunit protein kinase complex which contains equimolar ratios of 4 subunit types. The complex is a crucial glycogenolytic regulatory enzyme. This gene has two pseudogenes at chromosome 7q11.21 and one at chromosome 11p11.12. -
Synonyms
PHKG1;phosphorylase kinase, gamma 1 (muscle);PHKG;phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform;phosphorylase kinase gamma;phosphorylase kinase subunit gamma-1
Recombinant Proteins
- Human
- Mouse
- Chicken
- Rhesus macaque
- Rat
- E.coli
- Insect Cells
- Sf9 Cells
- Mammalian Cells
- HEK293
- Sf21 Cells
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
PHKG1 involved in several pathways and played different roles in them. We selected most pathways PHKG1 participated on our site, such as Calcium signaling pathway,Insulin signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PHKG1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Calcium signaling pathway | CYSLTR2,RYR1,CALM3B,VDAC2,ADCY2B,ERBB3,PRKCA,ERBB4A,ADRB2B,ATP2B4 |
| Insulin signaling pathway | SHC1,PIK3CD,FBP2,GYS1,G6PC,PPARGC1A,GSK3AA,PRKAR1A,PRKACBA,SOCS3 |
Protein Function
PHKG1 has several biochemical functions, for example, ATP binding,calmodulin binding,enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PHKG1 itself. We selected most functions PHKG1 had, and list some proteins which have the same functions with PHKG1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| phosphorylase kinase activity | PHKB,PHKG2,PHKG1B,PHKG1A,PHKA2 |
| calmodulin binding | ARPP21,MYH13,USP6,GEM,CALD1,MYLK,MTAP6,TTN,IQCB1,CAMK2B |
| ATP binding | MB21D1,Acsm2a,RTEL1,SMC1AL,RAF1A,ATP1A1A.2,FYNA,DNAJA3A,NEK3,PRKCHB |
| tau-protein kinase activity | MARK4,GSK3A,CDK5,MARK1,MARK2,CSNK1D,PHKG2,GSK3B,PRKAA1 |
| enzyme binding | PICK1,AKT1,PRKCH,PIAS1,VAPB,SCARB2,HSPA1A,ATP2A2,PARK2,UGT1A3 |
Interacting Protein
PHKG1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PHKG1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PHKG1.
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