PHC3
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Official Full Name
polyhomeotic homolog 3 (Drosophila) -
Overview
Polyhomeotic-like protein 3 is a protein that in humans is encoded by the PHC3 gene. -
Synonyms
PHC3;polyhomeotic homolog 3 (Drosophila);polyhomeotic like 3 (Drosophila);polyhomeotic-like protein 3;early development regulator 3;EDR3;FLJ12729;FLJ12967;HPH3;polyhomeotic like 3;Homolog of polyhomeotic 3;HPH 3;PH3;PHC 3;Polyhomeotic homolog 3;early development regulatory protein 3
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PHC3-1677H | Recombinant Human PHC3, GST-tagged | E.coli | Human | GST | 1-151aa | |
| PHC3-12712M | Recombinant Mouse PHC3 Protein | Mammalian Cells | Mouse | His |
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| PHC3-1343HCL | Recombinant Human PHC3 cell lysate | Human | Non |
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| PHC3-6680M | Recombinant Mouse PHC3 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| PHC3-6680M-B | Recombinant Mouse PHC3 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
PHC3 involved in several pathways and played different roles in them. We selected most pathways PHC3 participated on our site, such as Cellular Senescence,Cellular responses to stress,Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with PHC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Oxidative Stress Induced Senescence | SUZ12A,CBX8A,BMI1A,RNF2,KDM6B,SUZ12B,BMI1B,CBX8,PHC1,SCMH1 |
| SUMO E3 ligases SUMOylate target proteins | SMC6,CBX8,PHC2,CBX4,SMC5,EID3,NSMCE2,RNF2,SCMH1,PHC1 |
| SUMOylation | SCMH1,SENP5,SMC5,EID3,NSMCE1,NSMCE2,PHC2,UBA2,SENP1,RING1 |
| Cellular responses to stress | SUZ12B,CBX8,KIAA1967,RRAGA,HIST1H1A,MAPKAPK2B,CDK6,LC3,CHMP4B,GABARAPL2 |
| SUMOylation of DNA damage response and repair proteins | EID3,NSMCE1,NSMCE4A,PHC1,NSMCE2,SCMH1,CBX8,PHC2,SMC6,RNF2 |
| Metabolism of proteins | MUC20,B3GALTL,TIMM17A,COX17,MUC4,B3GNT6,ST3GAL3A,DPH1,C19orf10,B3GNT8 |
| Cellular Senescence | TERF2,HIST3H2BB,TINF2,RBBP7,AGO3,RNF2,E2F2,UBN1,H3F3D,TERF1 |
| Post-translational protein modification | TRAPPC6B,ADAMTS5,CTAGE5,ATPBD4,MUC5AC,MPDU1B,ARSJ,MLEC,WDR85,ST6GALNAC1.2 |
Protein Function
PHC3 has several biochemical functions, for example, DNA binding,protein binding,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PHC3 itself. We selected most functions PHC3 had, and list some proteins which have the same functions with PHC3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| zinc ion binding | SEC24D,ZNF257,RNF180,PHF23B,ADAT3,TAF3,ZDHHC13,PHC1,MT1G,LONRF3 |
| protein binding | CD22,CCDC88A,CEBPB,HOXD12,FUZ,PACS1,OSBPL3,CITED1,ROR1,DHRS2 |
| DNA binding | TERT,ETV5,TNP2,ORC6L,POLE3,ZFP580,SP5,GZF1,SIX7,INO80 |
Interacting Protein
PHC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PHC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PHC3.
OGT;BMI1;PCGF2;recB;CBX4;ALB;Bmi1;Cbx2
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