PHC3

  • Official Full Name

    polyhomeotic homolog 3 (Drosophila)

  • Overview

    Polyhomeotic-like protein 3 is a protein that in humans is encoded by the PHC3 gene.

  • Synonyms

    PHC3;polyhomeotic homolog 3 (Drosophila);polyhomeotic like 3 (Drosophila);polyhomeotic-like protein 3;early development regulator 3;EDR3;FLJ12729;FLJ12967;HPH3;polyhomeotic like 3;Homolog of polyhomeotic 3;HPH 3;PH3;PHC 3;Polyhomeotic homolog 3;early development regulatory protein 3
Cat.# Product name Source (Host) Species Tag Protein Length Price
PHC3-1677H Recombinant Human PHC3, GST-tagged E.coli Human GST 1-151aa
PHC3-12712M Recombinant Mouse PHC3 Protein Mammalian Cells Mouse His
PHC3-1343HCL Recombinant Human PHC3 cell lysate Human Non
PHC3-6680M Recombinant Mouse PHC3 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
PHC3-6680M-B Recombinant Mouse PHC3 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    PHC3 involved in several pathways and played different roles in them. We selected most pathways PHC3 participated on our site, such as Cellular Senescence,Cellular responses to stress,Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with PHC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolism of proteins O3far1,WDR85,APCS,SLC30A6,PCSK2,MPDU1A,DDIT3,C8orf84,TOMM22,CPB2
    SUMO E3 ligases SUMOylate target proteins RING1,SMC5,SMC6,NSMCE1,NSMCE2,NSMCE4A,RNF2,CBX4,PHC1,EID3
    Post-translational protein modification PHC2,CNIH3,ADAMTSL5,ADAMTSL3,CBX8,NANP,MUCL1,RING1,MLEC,MPDU1B
    Oxidative Stress Induced Senescence SUZ12B,CBX8A,EED,CBX6,TNIK,CBX6A,BMI1B,MINK1,PHC2,CBX8
    Cellular Senescence AGO1,SUZ12A,HTATIP,E2F3,HMGA1,Txn1,CBX6A,HIST1H1D,SUZ12,CDKN2C
    Cellular responses to stress CBX8B,MOV10,HIST1H1B,LAMTOR2,ATG7,RB1CC1,ATG9B,HSBP1B,CBX6,CDKN2C
    SUMOylation PHC1,RING1,PHC2,RNF2,SMC6,UBA2,SENP5,SAE1,EID3,SMC5
    SUMOylation of DNA damage response and repair proteins PHC2,RNF2,CBX8,NSMCE4A,SMC6,NSMCE2,NSMCE1,SCMH1,EID3,PHC1

    Protein Function

    PHC3 has several biochemical functions, for example, DNA binding,protein binding,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PHC3 itself. We selected most functions PHC3 had, and list some proteins which have the same functions with PHC3. You can find most of the proteins on our site.

    Function Related Protein
    protein binding OBFC1,MOCOS,DUSP23,KIF5A,DUT,CDK5RAP3,THG1L,EBF1,CRTC1,CYTH1
    DNA binding ZNF518A,MYCLB,RARAA,LIN28B,RARG,DMBX1A,HIST1H2AF,PROX1,FOXA2,TOP3A
    zinc ion binding SF1,TRIM3B,RARAA,LHX1A,CCS,MID2,JADE3,SQSTM1,RNF11A,APIP

    Interacting Protein

    PHC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PHC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PHC3.

    OGT;BMI1;PCGF2;recB;CBX4;ALB;Bmi1;Cbx2

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