PHACTR3
-
Official Full Name
phosphatase and actin regulator 3 -
Overview
The protein encoded by this gene is associated with the nuclear scaffold in proliferating cells. It was found to bind to the catalytic subunit of protein phosphatase-1 (PP1) and inhibit PP1 activity, suggesting that this protein may function as a regulatory subunit of PP1. Alternative splicing at this locus results in several transcript variants encoding different isoforms. -
Synonyms
PHACTR3;phosphatase and actin regulator 3;C20orf101, chromosome 20 open reading frame 101;C 20 orf 101;C20orf101;H 17739;H17739;MGC 117178;MGC117178;PHACTR 3;PHAR3_HUMAN;Scaffold associated PP1 inhibiting protein;Scaffold-associated PP1-inhibiting protein;SCAPIN 1;SCAPIN1;Scapinin;OTTHUMP00000031424;OTTHUMP00000031425;OTTHUMP00000031426;OTTHUMP00000174466;OTTHUMP00000174467;phosphatase and actin regulator 3, isoform 1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PHACTR3-4415R | Recombinant Rat PHACTR3 Protein | Mammalian Cells | Rat | His |
|
|
| PHACTR3-480HCL | Recombinant Human PHACTR3 lysate | HEK293 | Human | Non |
|
|
| PHACTR3-4075R | Recombinant Rat PHACTR3 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
|
|
| PHACTR3-4075R-B | Recombinant Rat PHACTR3 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
|
Involved Pathway
PHACTR3 involved in several pathways and played different roles in them. We selected most pathways PHACTR3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PHACTR3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
PHACTR3 has several biochemical functions, for example, actin binding,protein phosphatase 1 binding,protein phosphatase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PHACTR3 itself. We selected most functions PHACTR3 had, and list some proteins which have the same functions with PHACTR3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein phosphatase inhibitor activity | PPP1R35,ELFN2,PPP1R14B,ENSAA,PPP1R1C,SH3RF2,PTN,SET,PPP1R36,PPP1R10 |
| protein phosphatase type 1 regulator activity | NSFL1C,PHACTR1,PPP1R7,UBXN2A,PHACTR3A,PPP1R8,PPP1R15A,KCNS1,PHACTR3B,UBXN2B |
| protein phosphatase 1 binding | PHACTR4B,PAWR,PHACTR3A,PHACTR1,PPP1R9B,LILRB2,SHOC2,TCTEX1D4,PHACTR4,STAU1 |
| actin binding | CLMN,TNNT2A,SSH2B,MYH9A,MYOZ2,INO80,SMTN,PDLIM5,EPB41L3B,CNN3A |
Interacting Protein
PHACTR3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PHACTR3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PHACTR3.
LXN;PPP1CA;TAB1;MAPK6;q81ng4_bacan
Resources
Related Services
Related Products
References
