PGP
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Official Full Name
phosphoglycolate phosphatase -
Overview
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is 2-phosphoglycolate phosphohydrolase. Other names in common use include phosphoglycolate hydrolase, 2-phosphoglycolate phosphatase, P-glycolate phosphatase, and phosphoglycollate phosphatase. This enzyme participates in glyoxylate and dicarboxylate metabolism. -
Synonyms
PGP;phosphoglycolate phosphatase;PGPase;EC 3.1.3.18;MGC4692;EC 3.1.3
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Chicken
- Rat
- E.coli
- Mammalian Cells
- HEK293
- GST
- His&GST
- His
- Myc&DDK
- His&Fc&Avi
Involved Pathway
PGP involved in several pathways and played different roles in them. We selected most pathways PGP participated on our site, such as Glyoxylate and dicarboxylate metabolism,Metabolic pathways,Carbon metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PGP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | CHSY3,ALG9,ACSL1A,COX5B,GALNTL6,GPI,PAPSS1,ALDH2,NNMT,NDST3 |
| Glyoxylate and dicarboxylate metabolism | SHMT2,GCSHA,ACO1,GCSH,GLUL,GLYCTK,MDH1AA,PCCA,DLDH,MDH1 |
| Carbon metabolism | GPI,ME2,PFKL,G6PD,PRPS1B,HADHAB,ACADM,SDHDB,PCCB,ACAT1 |
Protein Function
PGP has several biochemical functions, for example, magnesium ion binding,nucleotide phosphatase activity, acting on free nucleotides,phosphoglycolate phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PGP itself. We selected most functions PGP had, and list some proteins which have the same functions with PGP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| nucleotide phosphatase activity, acting on free nucleotides | NUDT16,NTPCR,DUSP11 |
| protein tyrosine phosphatase activity | DUSP22,DUSP13,PTPRJA,PTPN9,PTPRUB,CDKN3,MTMR1B,PTPRG,PTPRNA,DUSP26 |
| magnesium ion binding | MARK2,ITPK1,NME1,ERN1,PRTFDC1,IMPA1,NLRC4,ATP8B5,ADSSL1,TSSK6 |
| phosphoglycolate phosphatase activity | APTX |
Interacting Protein
PGP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PGP here. Most of them are supplied by our site. Hope this information will be useful for your research of PGP.
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References
- Harpstrite, SE; Gu, H; et al. Interrogation of multidrug resistance (MDR1) P-glycoprotein (ABCB1) expression in human pancreatic carcinoma cells: correlation of Tc-99m-Sestamibi uptake with western blot analysis. NUCLEAR MEDICINE COMMUNICATIONS 35:1067-1070(2014).
- Liu, YD; Fan, XL; et al. Intraepidermal nerve fiber density of healthy human. NEUROLOGICAL RESEARCH 36:911-914(2014).
