PEMT
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Official Full Name
phosphatidylethanolamine N-methyltransferase -
Synonyms
PEMT;phosphatidylethanolamine N-methyltransferase;8830;ENSG00000133027;PNMT;PEAMT;PEMPT;PEMT2;17p11.2;MGC2483;phosphatidylethanolamine N-methyltransferase;phosphatidylethanolamine N-methyltransferase;EC 2.1.1.17
Recombinant Proteins
- Human
- Zebrafish
- Chicken
- Rat
- Mouse
- Mus musculus
- Bovine
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Non
- Avi
- Fc
- DDK
- Myc
Involved Pathway
PEMT involved in several pathways and played different roles in them. We selected most pathways PEMT participated on our site, such as Acetylcholine Synthesis,Glycerophospholipid biosynthesis,Glycerophospholipid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PEMT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycerophospholipid biosynthesis | ABHD3,BCHE,PHOSPHO1,CHKA,PLB1,AWAT2,PLD4,CPNE7,CEPT1,DGAT1B |
| Glycerophospholipid metabolism | PLA2G4AA,PNPLA7,GPD1,MBOAT7,ADPRM,PGS1,AGPAT9L,PLA2G10,MBOAT1,GPCPD1 |
| Metabolic pathways | MAN1C1,ISYNA1,TYMP,KL,MGAT3,EXT1A,PGD,GBA2,REV3L,ATP5A1 |
| Metabolism | CBLC-1,NAALAD2,UGT1B4,DGAT1B,SLC25A14,CA13,NUDT10,KCNC2,MOCOS,NOSIP |
| Synthesis of PC | ABHD3,PHOSPHO1,SLC44A5B,CEPT1,CEPT1A |
| Phospholipid metabolism | ABHD4,AWAT2,CPNE6,PITPNB,PLD6,ABHD3,PLBD1,SACM1LB,PNPLA8,CDS1 |
| Metabolism of lipids and lipoproteins | PLD6,NFYBA,COQ6,LPA,ARSH,APOEA,FA2H,TMEM195,EBP,APOF |
| Acetylcholine Synthesis | CHKA,CHAT |
Protein Function
PEMT has several biochemical functions, for example, phosphatidyl-N-dimethylethanolamine N-methyltransferase activity,phosphatidyl-N-methylethanolamine N-methyltransferase activity,phosphatidylethanolamine N-methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PEMT itself. We selected most functions PEMT had, and list some proteins which have the same functions with PEMT. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| phosphatidylethanolamine binding | ESYT2,ANXA11,MFGE8,PEBP1,LC3,NF1,CD300A |
Interacting Protein
PEMT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PEMT here. Most of them are supplied by our site. Hope this information will be useful for your research of PEMT.
Resources
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References
- Gao, X; van der Veen, JN; et al. Vagus nerve contributes to the development of steatohepatitis and obesity in phosphatidylethanolamine N-methyltransferase deficient mice. JOURNAL OF HEPATOLOGY 62:913-920(2015).
- Kohjima, M; Enjoji, M; et al. Pathophysiological analysis of primary biliary cirrhosis focusing on choline/phospholipid metabolism. LIVER INTERNATIONAL 35:1095-1102(2015).
