PDZD2
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Official Full Name
PDZ domain containing 2 -
Overview
Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. -
Synonyms
PDZD2;PDZ domain containing 2;PDZ domain containing 3 , PDZK3;PDZ domain-containing protein 2;KIAA0300;Activated in prostate cancer protein;AIPC;PAPIN;PDZ domain containing 3;PDZ domain containing protein 2;PDZ domain containing protein 3;PDZK 3;PIN1;Plakophilin related armadillo repeat protein interacting PDZ protein like;PDZ domain-containing protein 3;PDZK3
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
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| PDZD2-33H | Recombinant Human PDZD2 protein, His-tagged | E.coli | Human | His |
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| PDZD2-4364R | Recombinant Rat PDZD2 Protein | Mammalian Cells | Rat | His |
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| PDZD2-4024R | Recombinant Rat PDZD2 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| PDZD2-4024R-B | Recombinant Rat PDZD2 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
PDZD2 involved in several pathways and played different roles in them. We selected most pathways PDZD2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PDZD2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
PDZD2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by PDZD2 itself. We selected most functions PDZD2 had, and list some proteins which have the same functions with PDZD2. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
PDZD2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDZD2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PDZD2.
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References
- Linnemann, A; van der Ven, PFM; et al. The sarcomeric Z-disc component myopodin is a multiadapter protein that interacts with filamin and alpha-actinin. EUROPEAN JOURNAL OF CELL BIOLOGY 89:681-692(2010).
- Ardesjo, B; Portela-Gomes, GM; et al. Identification of a Novel Staining Pattern of Bile Duct Epithelial Cells in Primary Sclerosing Cholangitis. INFLAMMATORY BOWEL DISEASES 16:305-311(2010).
