PDC
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Official Full Name
phosducin -
Overview
This gene encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. This gene is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] -
Synonyms
PDC;phosducin;PHD;MEKA;PhLP;PhLOP;G beta gamma binding protein;phosducin-like orphan protein;33 kDa phototransducing protein
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PDC-12529M | Recombinant Mouse PDC Protein | Mammalian Cells | Mouse | His |
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| PDC-4318R | Recombinant Rat PDC Protein | Mammalian Cells | Rat | His |
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| PDC-3978R | Recombinant Rat PDC Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| PDC-3978R-B | Recombinant Rat PDC Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| PDC-6570M | Recombinant Mouse PDC Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| PDC-6570M-B | Recombinant Mouse PDC Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
PDC involved in several pathways and played different roles in them. We selected most pathways PDC participated on our site, such as Olfactory transduction,cyclic AMP biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Olfactory transduction | OR5V1,OR10C1,OR51B5,PRKG1,OR4D6,OR2L5,OR52B2,OLFR688,OLFR507,ANO2 |
| cyclic AMP biosynthesis | ARHGAP33,DOCK8,RAP1GAP2,RALGAPA1,GARNL3,RIC8 |
Protein Function
PDC has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by PDC itself. We selected most functions PDC had, and list some proteins which have the same functions with PDC. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
PDC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDC here. Most of them are supplied by our site. Hope this information will be useful for your research of PDC.
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References
- Dosenovic, P; Adori, M; et al. Slc15a4 function is required for intact class switch recombination to IgG2c in response to TLR9 stimulation. IMMUNOLOGY AND CELL BIOLOGY 93:136-146(2015).
- Lahiani, A; Zahavi, E; et al. Human PLacental eXpanded (PLX) mesenchymal-like adherent stromal cells confer neuroprotection to nerve growth factor (NGF)-differentiated PC12 cells exposed to ischemia by secretion of IL-6 and VEGF. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1853:422-430(2015).
