PCYT1B
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Official Full Name
phosphate cytidylyltransferase 1, choline, beta -
Overview
The protein encoded by this gene belongs to the cytidylyltransferase family. It is involved in the regulation of phosphatidylcholine biosynthesis. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. -
Synonyms
PCYT1B;phosphate cytidylyltransferase 1, choline, beta;phosphate cytidylyltransferase 1, choline, beta isoform;choline-phosphate cytidylyltransferase B;CCT beta;CTB;CCT B;CCTB;CT B;CTP:phosphocholine cytidylyltransferase B;Phosphorylcholine transferase B;CCT-beta
Recombinant Proteins
- Rhesus macaque
- Rat
- Mouse
- Human
- Mammalian Cell
- E.coli
- HEK293
- HEK293T
- His
- Non
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PCYT1B-3336R | Recombinant Rhesus monkey PCYT1B Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| PCYT1B-4315R | Recombinant Rat PCYT1B Protein | Mammalian Cell | Rat | His |
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| PCYT1B-1319HCL | Recombinant Human PCYT1B cell lysate | Non |
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| Pcyt1b-1929M | Recombinant Mouse Pcyt1b Protein, His-tagged | E.coli | Mouse | His | His62-Thr295 |
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| PCYT1B-3154R | Recombinant Rhesus Macaque PCYT1B Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| PCYT1B-3154R-B | Recombinant Rhesus Macaque PCYT1B Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| PCYT1B-3975R | Recombinant Rat PCYT1B Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| PCYT1B-3975R-B | Recombinant Rat PCYT1B Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| Pcyt1b-4725M | Recombinant Mouse Pcyt1b Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| PCYT1B-6364H | Recombinant Human PCYT1B Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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Involved Pathway
PCYT1B involved in several pathways and played different roles in them. We selected most pathways PCYT1B participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PCYT1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
PCYT1B has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by PCYT1B itself. We selected most functions PCYT1B had, and list some proteins which have the same functions with PCYT1B. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
PCYT1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PCYT1B here. Most of them are supplied by our site. Hope this information will be useful for your research of PCYT1B.
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References
- Bapiro, TE; Frese, KK; et al. Gemcitabine diphosphate choline is a major metabolite linked to the Kennedy pathway in pancreatic cancer models in vivo. BRITISH JOURNAL OF CANCER 111:318-325(2014).
- Lee, JY; Johnson, J; et al. Crystal Structure of a Mammalian CTP: Phosphocholine Cytidylyltransferase Catalytic Domain Reveals Novel Active Site Residues within a Highly Conserved Nucleotidyltransferase Fold. JOURNAL OF BIOLOGICAL CHEMISTRY 284:33535-33548(2009).
