PCSK1N
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Official Full Name
proprotein convertase subtilisin/kexin type 1 inhibitor -
Overview
Members of the subtilisin-like proprotein convertase family process latent precursor proteins into their biologically active products. The protein encoded by this gene appears to function as an endogenous inhibitor of proprotein convertase subtilisin/kexin type 1. -
Synonyms
PCSK1N;proprotein convertase subtilisin/kexin type 1 inhibitor;proSAAS;SAAS;pro-SAAS;proprotein convertase 1 inhibitor;granin-like neuroendocrine peptide
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- Mammalian cells
- HEK293T
- His
- Non
- His&Fc&Avi
- Flag
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PCSK1N-2488H | Recombinant human PCSK1N, His-tagged | E.coli | Human | His |
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| PCSK1N-4306R | Recombinant Rat PCSK1N Protein | Mammalian Cell | Rat | His |
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| PCSK1N-1316HCL | Recombinant Human PCSK1N cell lysate | Human | Non |
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| PCSK1N-1621H | Recombinant Human PCSK1N Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| PCSK1N-1621H-B | Recombinant Human PCSK1N Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| PCSK1N-2018HFL | Recombinant Full Length Human PCSK1N Protein, C-Flag-tagged | Mammalian cells | Human | Flag | Full L. |
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| PCSK1N-3967R | Recombinant Rat PCSK1N Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| PCSK1N-3967R-B | Recombinant Rat PCSK1N Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| Pcsk1n-4720M | Recombinant Mouse Pcsk1n Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| PCSK1N-5677H | Recombinant Human PCSK1N Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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Involved Pathway
PCSK1N involved in several pathways and played different roles in them. We selected most pathways PCSK1N participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PCSK1N were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
PCSK1N has several biochemical functions, for example, endopeptidase inhibitor activity,receptor binding,serine-type endopeptidase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PCSK1N itself. We selected most functions PCSK1N had, and list some proteins which have the same functions with PCSK1N. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| endopeptidase inhibitor activity | C3A.2,Serpina1c,C4A,C3A.6,TFPI,PROS1,C3B.2,SERPINA1D,RECK,PSMF1 |
| receptor binding | FGF20B,KCNA5,ANXA1,CADM2,WNT2BA,Itga10&Itgb1,A2M,C3,PICK1,NTF7 |
| serine-type endopeptidase inhibitor activity | WFDC12,SERPINA11,SERPINB5,RECK,A2M,SERPINA3M,GOPC,SERPINE2,SPINK3,A2ML1 |
Interacting Protein
PCSK1N has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PCSK1N here. Most of them are supplied by our site. Hope this information will be useful for your research of PCSK1N.
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References
- Berger, JM; Vaillant, N; et al. PCSK9-deficiency does not alter blood pressure and sodium balance in mouse models of hypertension. ATHEROSCLEROSIS 239:252-259(2015).
- de Keyser, CE; Becker, ML; et al. The rs13064411 polymorphism in the WDR52 gene, associated with PCSK9 levels, modifies statin-induced changes in serum total and LDL cholesterol levels. PHARMACOGENETICS AND GENOMICS 25:134-142(2015).
