PCGF1
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Official Full Name
polycomb group ring finger 1 -
Overview
PCGF1 is a mammalian homolog of the Drosophila polycomb group genes, which act as transcriptional repressors to regulate anterior-posterior patterning in early embryonic development (Nunes et al., 2001 [PubMed 11287196]). See also PCGF2 (MIM 600346).[supplied by OMIM, Aug 2008] -
Synonyms
PCGF1;polycomb group ring finger 1;NSPC1;RNF68;RNF3A-2;2010002K04Rik;polycomb group RING finger protein 1;RING finger protein 68;nervous system Polycomb-1
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Rat
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- His
- Non
- GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PCGF1-1574H | Recombinant Human PCGF1, His-tagged | E.coli | Human | His | 1-247aa | |
| PCGF1-12489M | Recombinant Mouse PCGF1 Protein | Mammalian Cells | Mouse | His |
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| PCGF1-1648Z | Recombinant Zebrafish PCGF1 | Mammalian Cells | Zebrafish | His |
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| PCGF1-4297R | Recombinant Rat PCGF1 Protein | Mammalian Cells | Rat | His |
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| PCGF1-1308HCL | Recombinant Human PCGF1 cell lysate | Human | Non |
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| PCGF1-20HFL | Recombinant Full Length Human PCGF1 Protein, GST-tagged | Wheat Germ | Human | GST | Full L. 1-247 aa |
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| PCGF1-3959R | Recombinant Rat PCGF1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| PCGF1-3959R-B | Recombinant Rat PCGF1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| PCGF1-6548M | Recombinant Mouse PCGF1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| PCGF1-6548M-B | Recombinant Mouse PCGF1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
PCGF1 involved in several pathways and played different roles in them. We selected most pathways PCGF1 participated on our site, such as Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with PCGF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Signaling pathways regulating pluripotency of stem cells | LIF,ID4,INHBB,PIK3CA,SOX2,FGFR2,OTX1,PIK3R5,WNT7A,APC |
Protein Function
PCGF1 has several biochemical functions, for example, protein C-terminus binding,protein binding,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PCGF1 itself. We selected most functions PCGF1 had, and list some proteins which have the same functions with PCGF1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ZNF193,KIAA0319L,FAM86C,PSMB2,PYROXD1,FBP2,BEND7,DDO,ARL2,SORL1 |
| zinc ion binding | WHSC1L1,ALPI,L3MBTL4,C6AST3,PEG10,RNF40,MMEL1,MORC3,PHF17,PDLIM1 |
| protein C-terminus binding | HOMER3,CTNNB1,KPNA3,TJP2,DBNL,LIG4,HPCAL4,CDC37,CAV3,ERCC2 |
Interacting Protein
PCGF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PCGF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PCGF1.
RNF2;BCOR;RING1;CBX8;CBX6
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