PAXIP1

  • Official Full Name

    PAX interacting (with transcription-activation domain) protein 1

  • Overview

    This gene is a member of the paired box (PAX) gene family and encodes a nuclear protein with six BRCT (breast cancer carboxy-terminal) domains. This protein plays a critical role in maintaining genome stability, condensation of chromatin and progression through mitosis. [provided by RefSeq, Jul 2008]

  • Synonyms

    PAXIP1;PAX interacting (with transcription-activation domain) protein 1;PTIP;TNRC2;CAGF28;CAGF29;PACIP1;PAXIP1L;PAX-interacting protein 1;protein encoded by CAG trinucleotide repeats;PAX transcription activation domain interacting protein 1 like
Cat.# Product name Source (Host) Species Tag Protein Length Price
PAXIP1-3751H Recombinant Human PAXIP1 protein, His-tagged E.coli Human His 717-1069 aa
PAXIP1-12399M Recombinant Mouse PAXIP1 Protein Mammalian Cell Mouse His
PAXIP1-1463Z Recombinant Zebrafish PAXIP1 Mammalian Cell Zebrafish His
PAXIP1-3410HCL Recombinant Human PAXIP1 293 Cell Lysate HEK293 Human Non
PAXIP1-6521M Recombinant Mouse PAXIP1 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
PAXIP1-6521M-B Recombinant Mouse PAXIP1 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    PAXIP1 involved in several pathways and played different roles in them. We selected most pathways PAXIP1 participated on our site, such as DNA Double-Strand Break Repair,DNA Repair,Nonhomologous End-Joining (NHEJ), which may be useful for your reference. Also, other proteins which involved in the same pathway with PAXIP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Nonhomologous End-Joining (NHEJ) TDP2,TDP1,TDP2B,RIF1
    DNA Double-Strand Break Repair KDM4B,TIMELESS,KDM4A,PPP4R2,EYA4,RAD50,RNF4,POLD3,PPP4CB,EYA2
    DNA Repair MGMT,COPS8,ZFP830,COPS5,THRSP,INO80,RAD9,COPS7B,GEN1,UBE2L6

    Protein Function

    PAXIP1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PAXIP1 itself. We selected most functions PAXIP1 had, and list some proteins which have the same functions with PAXIP1. You can find most of the proteins on our site.

    Function Related Protein
    protein binding ZC3H15,ZNF567,NEUROG1,a,MYO5A,ATXN3,GALR1,UCHL1,RCHY1,WDR92

    Interacting Protein

    PAXIP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PAXIP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PAXIP1.

    TP53BP1;PAGR1;ASH2L;A2M;UMPS;TCN2;SMAD2;ectB;ZBTB8A

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