PAX1
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Official Full Name
paired box 1 -
Overview
This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically;contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development.;This gene plays a role in pattern formation during embryogenesis and may be essential for development of the vertebral;column. This gene is silenced by methylation in ovarian and cervical cancers and may be a tumor suppressor gene.;Mutations in this gene are also associated with vertebral malformations. -
Synonyms
PAX1;paired box 1;paired box gene 1;paired box protein Pax-1;HUP48;OTTHUMP00000030407;Paired box protein Pax 1;Paired domain gene HuP48;PAX 1;PAX1_HUMAN;OTTHUMP00000206906
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PAX1-12390M | Recombinant Mouse PAX1 Protein | Mammalian Cell | Mouse | His |
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| PAX1-316H | Recombinant Human PAX1 | Mammalian Cell | Human | His |
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| PAX1-3799H | Recombinant Human PAX1 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| PAX1-3799H-B | Recombinant Human PAX1 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| PAX1-6515M | Recombinant Mouse PAX1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| PAX1-6515M-B | Recombinant Mouse PAX1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
PAX1 involved in several pathways and played different roles in them. We selected most pathways PAX1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PAX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
PAX1 has several biochemical functions, for example, DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PAX1 itself. We selected most functions PAX1 had, and list some proteins which have the same functions with PAX1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | SIX7,JUNB,ZNF329,THAP3,TIGD3,POLE4,MEOX2B,POU5F3,Ar,POLM |
Interacting Protein
PAX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PAX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PAX1.
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