PANK4
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Official Full Name
pantothenate kinase 4 -
Overview
This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is most abundant in muscle but is expressed in all tissues. -
Synonyms
PANK4;pantothenate kinase 4;FLJ10782;hPanK4;pantothenic acid kinase 4;DKFZp547M242
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Rat
- Chicken
- Cynomolgus
- E.coli
- Mammalian Cell
- HEK293
- His
- Non
- His&Fc&Avi
Involved Pathway
PANK4 involved in several pathways and played different roles in them. We selected most pathways PANK4 participated on our site, such as Pantothenate and CoA biosynthesis,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PANK4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Pantothenate and CoA biosynthesis | COASY,AASDHPPT,VNN2,DPYDB,DPYD,PANK2,DPYS,PANK3,PANK1B,ENPP1 |
| Metabolic pathways | DGKD,EPRS,SI,UROD,TUSC3,TGDS,RGN,PFAS,PON3,ARG1 |
Protein Function
PANK4 has several biochemical functions, for example, ATP binding,pantothenate kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PANK4 itself. We selected most functions PANK4 had, and list some proteins which have the same functions with PANK4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| pantothenate kinase activity | PANK1,PANK1B,PANK3,PANK2 |
| ATP binding | UCK2A,KIF18B,CENPE,HSPA12A,HUNK,CKMT2B,APAF1,CCT8,ACVR1BA,MYO9B |
Interacting Protein
PANK4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PANK4 here. Most of them are supplied by our site. Hope this information will be useful for your research of PANK4.
PEA15
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References
- Deperas-Kaminska, M; Bajinskis, A; et al. RADIATION-INDUCED CHANGES IN LEVELS OF SELECTED PROTEINS IN PERIPHERAL BLOOD SERUM OF BREAST CANCER PATIENTS AS A POTENTIAL TRIAGE BIODOSIMETER FOR LARGE-SCALE RADIOLOGICAL EMERGENCIES. HEALTH PHYSICS 107:555-563(2014).
- Dwarakanath, S; Zafar, A; et al. Does lesioning surgery have a role in the management of multietiological tremor in the era of Deep Brain Stimulation?. CLINICAL NEUROLOGY AND NEUROSURGERY 125:131-136(2014).
