PAIP2B
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Official Full Name
poly(A) binding protein interacting protein 2B -
Overview
Most mRNAs, except for histones, contain a 3-prime poly(A) tail. Poly(A)-binding protein (PABP; see MIM 604679);enhances translation by circularizing mRNA through its interaction with the translation initiation factor EIF4G1 (MIM;600495) and the poly(A) tail. Various PABP-binding proteins regulate PABP activity, including PAIP1 (MIM 605184), a;translational stimulator, and PAIP2A (MIM 605604) and PAIP2B, translational inhibitors (Derry et al., 2006 (PubMed;17381337)). -
Synonyms
PAIP2B;poly(A) binding protein interacting protein 2B;polyadenylate-binding protein-interacting protein 2B;KIAA1155;PABP-interacting protein 2B;PAI2B_HUMAN;PAIP-2B;Poly(A)-binding protein-interacting protein 2B
Recombinant Proteins
- Zebrafish
- Mouse
- Rhesus macaque
- Mammalian Cells
- HEK293
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PAIP2B-11029Z | Recombinant Zebrafish PAIP2B | Mammalian Cells | Zebrafish | His |
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| PAIP2B-12316M | Recombinant Mouse PAIP2B Protein | Mammalian Cells | Mouse | His |
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| PAIP2B-3289R | Recombinant Rhesus monkey PAIP2B Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| PAIP2B-3107R | Recombinant Rhesus Macaque PAIP2B Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| PAIP2B-3107R-B | Recombinant Rhesus Macaque PAIP2B Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| PAIP2B-6472M | Recombinant Mouse PAIP2B Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| PAIP2B-6472M-B | Recombinant Mouse PAIP2B Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
PAIP2B involved in several pathways and played different roles in them. We selected most pathways PAIP2B participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PAIP2B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
PAIP2B has several biochemical functions, for example, poly(A) binding,translation repressor activity, nucleic acid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PAIP2B itself. We selected most functions PAIP2B had, and list some proteins which have the same functions with PAIP2B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| translation repressor activity, nucleic acid binding | CPEB3,CPEB4,CELF4,CPEB1,CPEB1B,PPP1R2P9,PURA,CPEB1A,CPEB2,CELF1 |
| poly(A) binding | EIF4A3,KHDRBS2,PABPC3,PABPC4,SYNCRIP,PABPC1,HNRPDL,KHDRBS1,ZC3H14,DDX3X |
Interacting Protein
PAIP2B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PAIP2B here. Most of them are supplied by our site. Hope this information will be useful for your research of PAIP2B.
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