PAIP1
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Official Full Name
poly(A) binding protein interacting protein 1 -
Overview
The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. -
Synonyms
PAIP1;poly(A) binding protein interacting protein 1;polyadenylate-binding protein-interacting protein 1;PAIP-1;PABP-interacting protein 1;PABC1-interacting protein 1;poly(A)-binding protein-interacting protein 1;polyadenylate binding protein-intera
Recombinant Proteins
- Human
- Rhesus macaque
- Chicken
- Zebrafish
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Non
- Avi
- Fc
- DDK
- Myc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PAIP1-1512H | Recombinant Human PAIP1, GST-tagged | E.coli | Human | GST | C-term-300aa | |
| PAIP1-3287R | Recombinant Rhesus monkey PAIP1 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| PAIP1-5425C | Recombinant Chicken PAIP1 | Mammalian Cells | Chicken | His |
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| PAIP1-5426C | Recombinant Chicken PAIP1 | Mammalian Cells | Chicken | His |
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| PAIP1-945Z | Recombinant Zebrafish PAIP1 | Mammalian Cells | Zebrafish | His |
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| PAIP1-3460HCL | Recombinant Human PAIP1 293 Cell Lysate | HEK293 | Human | Non |
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| PAIP1-3105R | Recombinant Rhesus Macaque PAIP1 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | Avi&Fc&His |
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| PAIP1-3105R-B | Recombinant Rhesus Macaque PAIP1 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| Paip1-4661M | Recombinant Mouse Paip1 Protein, Myc/DDK-tagged | HEK293 | Mouse | DDK&Myc |
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Involved Pathway
PAIP1 involved in several pathways and played different roles in them. We selected most pathways PAIP1 participated on our site, such as Deadenylation of mRNA,Deadenylation-dependent mRNA decay,Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with PAIP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Deadenylation-dependent mRNA decay | EXOSC8,DCP2,NT5C3B,EIF4A1,TNKS1BP1,LSM6,C2orf29,DDX6,EIF4A2,EIF4B |
| Deadenylation of mRNA | TNKS1BP1,D1BWG0212E,EIF4B,EIF4E,EIF4A2,EIF4G1,C2orf29,EIF4EB,EIF4A1 |
| Gene Expression | DARS,COX5B,ZNF493,DNAJC8,ZNF566,TRIM28,NRBF2B,TH1L,ZNF649,CSTF3 |
| Translation Factors | EEF1B2,EEF1A2,EEF1D,EIF2B1,EIF1,EEF1G,EIF4EBP2,EEF2B,EIF5A |
| RNA transport | EIF4BA,NUP85,ALYREF,MAGOH,SUMO2B,SUMO4,NUP88,EIF5B,PABPC3,NXF2 |
Protein Function
PAIP1 has several biochemical functions, for example, RNA binding,protein binding,translation activator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PAIP1 itself. We selected most functions PAIP1 had, and list some proteins which have the same functions with PAIP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | MAGEF1,RBBP4,SEC23IP,ROPN1,USP34,GJD3,C17orf28,MAP3K8,CORO1B,CSRNP2 |
| RNA binding | DROSHA,EIF4H,UNC50,RDBP,LOC81691,JMJD6,ILF3,HNRNPA1L2,BARD1,PABPC1B |
| translation activator activity | PABPC1,DAZL,BOLL,LARP1,RPS27L,ABCF1 |
Interacting Protein
PAIP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PAIP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PAIP1.
PABPC1;Pabpc1;Eif4a1
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References
- Taleat, Z; Cristea, C; et al. Electrochemical immunoassay based on aptamer-protein interaction and functionalized polymer for cancer biomarker detection. JOURNAL OF ELECTROANALYTICAL CHEMISTRY 717:119-124(2014).
- Bergeron, D; Lapointe, C; et al. An Out-of-frame Overlapping Reading Frame in the Ataxin-1 Coding Sequence Encodes a Novel Ataxin-1 Interacting Protein. JOURNAL OF BIOLOGICAL CHEMISTRY 288:-(2013).
