P2RY13
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Official Full Name
purinergic receptor P2Y, G-protein coupled, 13 -
Overview
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is activated by ADP. -
Synonyms
P2RY13;purinergic receptor P2Y, G-protein coupled, 13;G protein coupled receptor 86 , GPR86, GPR94;P2Y purinoceptor 13;FKSG77;P2Y13;G protein coupled receptor 86;G protein coupled receptor 94;G-protein coupled receptor 86;G-protein coupled receptor 94;GPCR1;GPR86;GPR94;HGNC:13661;P2Y13_HUMAN;Purinergic receptor P2Y G protein coupled 13;SP174;OTTHUMP00000208577;G protein-coupled receptor 86
Recombinant Proteins
- Mouse
- Rat
- Human
- Macaca fascicularis
- Mammalian Cell
- HEK293
- E.coli expression system
- His
- Non
- His&Fc&Avi
Involved Pathway
P2RY13 involved in several pathways and played different roles in them. We selected most pathways P2RY13 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with P2RY13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neuroactive ligand-receptor interaction | ADRB3A,NR3C1,P2RY11,PTH1RA,ADORA2AB,P2RY8,HCRTR1,TSHR,LPAR2,GNRHR2 |
Protein Function
P2RY13 has several biochemical functions, for example, G-protein coupled purinergic nucleotide receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by P2RY13 itself. We selected most functions P2RY13 had, and list some proteins which have the same functions with P2RY13. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| G-protein coupled purinergic nucleotide receptor activity | P2RY8,P2RY2,P2RY10,GPR171,PTAFR,P2RY4,P2RY1,P2RY11,GPR34B,P2RY6 |
Interacting Protein
P2RY13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with P2RY13 here. Most of them are supplied by our site. Hope this information will be useful for your research of P2RY13.
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References
- Chatterjee, C; Sparks, DL; et al. Hepatic Lipase Release is Inhibited by a Purinergic Induction of Autophagy. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY 33:883-894(2014).
- Hennen, S; Wang, HB; et al. Decoding Signaling and Function of the Orphan G Protein-Coupled Receptor GPR17 with a Small-Molecule Agonist. SCIENCE SIGNALING 6:-(2013).
