P2RY11
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Official Full Name
purinergic receptor P2Y, G-protein coupled, 11 -
Overview
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is coupled to the stimulation of the phosphoinositide and adenylyl cyclase pathways and behaves as a selective purinoceptor. Naturally occuring read-through transcripts, resulting from intergenic splicing between this gene and an immediately upstream gene (PPAN, encoding peter pan homolog), have been found. The PPAN-P2RY11 read-through mRNA is ubiquitously expressed and encodes a fusion protein that shares identity with each individual gene product. -
Synonyms
P2RY11;purinergic receptor P2Y, G-protein coupled, 11;P2Y purinoceptor 11;P2Y11;P2Y11 receptor;Purinergic receptor P2Y G protein coupled 11;Purinergic receptor P2Y11
Recombinant Proteins
- Human
- Rhesus macaque
- Zebrafish
- E.coli
- Mammalian Cell
- HEK293
- E.coli expression system
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| P2RY11-1496H | Recombinant Human P2RY11, GST-tagged | E.coli | Human | GST | C-110aa | |
| P2RY11-3271R | Recombinant Rhesus monkey P2RY11 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| P2RY11-8017Z | Recombinant Zebrafish P2RY11 | Mammalian Cell | Zebrafish | His |
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| P2RY11-3493HCL | Recombinant Human P2RY11 293 Cell Lysate | HEK293 | Human | Non |
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| P2RY11-3089R | Recombinant Rhesus Macaque P2RY11 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| P2RY11-3089R-B | Recombinant Rhesus Macaque P2RY11 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| RFL10793HF | Recombinant Full Length Human P2Y Purinoceptor 11(P2Ry11) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length (1-374) |
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Involved Pathway
P2RY11 involved in several pathways and played different roles in them. We selected most pathways P2RY11 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with P2RY11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neuroactive ligand-receptor interaction | TAAR14H,NPY1R,OPRM1,NTSR1,F2,GRIN2A,GABRA2,P2RX4,HCRTR1,TAAR10A |
Protein Function
P2RY11 has several biochemical functions, for example, ATP-activated adenosine receptor activity,G-protein coupled purinergic nucleotide receptor activity,neurotransmitter receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by P2RY11 itself. We selected most functions P2RY11 had, and list some proteins which have the same functions with P2RY11. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| receptor activity | EDAR,SIGLEC7,CADM4,PAQR3B,Tnfrsf22,TREM2,RRBP1B,STRA6,TNFRSF11B,IL10RB |
| neurotransmitter receptor activity | GRIN3B |
| ATP-activated adenosine receptor activity | P2RY1 |
| G-protein coupled purinergic nucleotide receptor activity | P2RY2,P2RY14,P2RY1,PTAFR,P2RY10,GPR34B,P2RY6,P2RY13,GPR171,P2RY4 |
Interacting Protein
P2RY11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with P2RY11 here. Most of them are supplied by our site. Hope this information will be useful for your research of P2RY11.
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