P2RX5
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Official Full Name
purinergic receptor P2X, ligand-gated ion channel, 5 -
Overview
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream gene, TAX1BP3 (Tax1 binding protein 3). -
Synonyms
P2RX5;purinergic receptor P2X, ligand-gated ion channel, 5;P2X purinoceptor 5;P2X5;ATP receptor;ATP receptor subunit;ionotropic ATP receptor P2X5;MGC47755;P2X5R;Purinergic receptor;Purinergic receptor P2X ligand gated ion channel 5;OTTHUMP00000115870;OTTHUMP00000241718;OTTHUMP00000241719;OTTHUMP00000241720;OTTHUMP00000241722;OTTHUMP00000241723;lymphoid-restricted histocompatibility antigen-1;LRH-1
Recombinant Proteins
- Human
- Rat
- Chicken
- Zebrafish
- E.coli
- Mammalian Cell
- HEK293
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| P2RX5-1492H | Recombinant Human P2RX5, GST-tagged | E.coli | Human | GST | 52-422aa | |
| P2RX5-4230R | Recombinant Rat P2RX5 Protein | Mammalian Cell | Rat | His |
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| P2RX5-6313C | Recombinant Chicken P2RX5 | Mammalian Cell | Chicken | His |
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| P2RX5-9763Z | Recombinant Zebrafish P2RX5 | Mammalian Cell | Zebrafish | His |
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| P2RX5-3497HCL | Recombinant Human P2RX5 293 Cell Lysate | HEK293 | Human | Non |
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| P2RX5-3498HCL | Recombinant Human P2RX5 293 Cell Lysate | HEK293 | Human | Non |
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| P2RX5-2538H | Recombinant Human P2RX5 Protein, His-tagged | E.coli | Human | His | Lys52-Arg319 |
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| P2RX5-3892R | Recombinant Rat P2RX5 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| P2RX5-3892R-B | Recombinant Rat P2RX5 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
P2RX5 involved in several pathways and played different roles in them. We selected most pathways P2RX5 participated on our site, such as Calcium signaling pathway,Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with P2RX5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Calcium signaling pathway | HTR7,ITPKC,BDKRB2,CAMK2G,PLCD1A,AKR1C1,STIM1A,PRKCG,HTR5A,P2RX4A |
| Neuroactive ligand-receptor interaction | TAAR4,GRIN3B,GABRG3,CHRND,GRM7,CHRNB1,GABRR3,ADORA1,CHRNA2A,PTGFR |
Protein Function
P2RX5 has several biochemical functions, for example, ATP binding,extracellular ATP-gated cation channel activity,ion channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by P2RX5 itself. We selected most functions P2RX5 had, and list some proteins which have the same functions with P2RX5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ion channel activity | CLCN4-2,ITPR1,TRPN1,SCN1LAB,KCNC3B,ITPR3,KCNV2,TRPM4C,KCNV2B,FXYD7 |
| transmembrane signaling receptor activity | ERBB3,BAI2,OR4C12,TNFRSF10D,GPR126,OR4F29,M6PR,TRPV1,LAG3,FZD7A |
| purinergic nucleotide receptor activity | P2RX4,P2RX4A,P2RX3A,P2RX6,P2RX1,NNR,P2RX7,P2RX2,P2RX8,P2RX3B |
| extracellular ATP-gated cation channel activity | P2RX8,P2RX4,P2RX3B,NNR,P2RX6,P2RX7,P2RX3,P2RX4B,P2RX3A,P2RX2 |
| ATP binding | MATK,PSKH2,HLTF,CLCN6,PEX6,MYH6,KITB,MYO1F,SPAST,EIF2B2 |
Interacting Protein
P2RX5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with P2RX5 here. Most of them are supplied by our site. Hope this information will be useful for your research of P2RX5.
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