OXTR
-
Official Full Name
oxytocin receptor -
Overview
The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition. -
Synonyms
OXTR;oxytocin receptor;OT-R
Recombinant Proteins
- Chicken
- Rhesus macaque
- Rat
- Zebrafish
- Human
- Mouse
- Bovine
- Sheep
- Sus scrofa (Pig)
- Mus musculus
- Macaca mulatta
- Mammalian Cells
- E.coli
- HEK293
- His
- GST
- Non
- Avi
- Fc
Involved Pathway
OXTR involved in several pathways and played different roles in them. We selected most pathways OXTR participated on our site, such as Calcium signaling pathway,cAMP signaling pathway,Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with OXTR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| cAMP signaling pathway | NFKB1,FOS,CALML3,AKT1,GNAI1,ATP2B4,ACOX1,CALM1,GABBR1,PRKACG |
| Calcium signaling pathway | PDE1B,CALML3,GRIN2D,CACNA1D,SLC25A31,AVPR1A,PTK2B,SPHK1,TACR3,AVPR1B |
| Oxytocin signaling pathway | PRKAA1,CACNG1,MAP2K1,PIK3CG,ELK1,PTGS2,GUCY1B3,GNAS,PIK3R1,MAPK7 |
| Neuroactive ligand-receptor interaction | HTR6,GABRA4,HCRTR1,LTB4R2,CSH2,VIPR1,GRIN2BB,NR3C1,P2RX4A,HTR4 |
Protein Function
OXTR has several biochemical functions, for example, oxytocin receptor activity,peptide binding,peptide hormone binding. Some of the functions are cooperated with other proteins, some of the functions could acted by OXTR itself. We selected most functions OXTR had, and list some proteins which have the same functions with OXTR. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| peptide binding | TPP1,THOP1,HCRTR2,ERAP2,FURIN,CTSL2,PPIB,OXTRL,CRIP1,Ctsl |
| oxytocin receptor activity | OXTRL |
| peptide hormone binding | MC3R,PTH1R,HCRTR1,ACVR1,GHR,EDNRB,CRHR2,AGTR1B,NPR2,PTH1RB |
Interacting Protein
OXTR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OXTR here. Most of them are supplied by our site. Hope this information will be useful for your research of OXTR.
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