Otof
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Official Full Name
Otoferlin -
Overview
Otoferlin is a protein that in humans is encoded by the OTOF gene. Mutations in this gene are a cause of neurosensory nonsyndromic recessive deafness, DFNB9. The short form of the encoded protein has 3 C2 domains, a single carboxy-terminal transmembrane d -
Synonyms
Otoferlin;OTOF;AUNB1;DFNB6;DFNB9;FER1L2;NSRD9
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| OTOF-12226M | Recombinant Mouse OTOF Protein | Mammalian Cells | Mouse | His |
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| OTOF-5763H | Recombinant Human OTOF protein, His-tagged | E.coli | Human | His | 1461-1868aa |
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| OTOF-6427M | Recombinant Mouse OTOF Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| OTOF-6427M-B | Recombinant Mouse OTOF Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| Otof-7252M | Recombinant Mouse Otof protein(1461-1868aa), His&Myc-tagged | E.coli | Mouse | N-His&C-Myc | 1461-1868aa |
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Involved Pathway
Otof involved in several pathways and played different roles in them. We selected most pathways Otof participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with Otof were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
Otof has several biochemical functions, for example, AP-2 adaptor complex binding,calcium ion binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Otof itself. We selected most functions Otof had, and list some proteins which have the same functions with Otof. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | JDP2,APOOL,EIF4EBP2,SEPT10,TES,TEX19.1,CTNNA1,TXNDC9,BCL2L2,RAB8B |
| calcium ion binding | SCIN,DNASE1L2,CDH11,CDH8,PCDHGC5,MICU2,SLC25A23,TPD52,PKD1L2,CAPN8 |
| protein complex binding | HSPD1,RAN,ITPR1,RRAS,MLC1,PROS1,ANKRD54,CCNE1,SH2B3,PCSK2 |
| AP-2 adaptor complex binding | AAK1,TBC1D5,FCHO1,ARRB1,LDLRAP1 |
Interacting Protein
Otof has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Otof here. Most of them are supplied by our site. Hope this information will be useful for your research of Otof.
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