OSBPL1A
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Official Full Name
oxysterol binding protein-like 1A -
Overview
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Transcript variants derived from alternative promoter usage and/or alternative splicing exist; they encode different isoforms. -
Synonyms
OSBPL1A;oxysterol binding protein-like 1A;OSBPL1B, oxysterol binding protein like 1B;oxysterol-binding protein-related protein 1;ORP 1;ORP1;OSBP-related protein 1;oxysterol binding protein-like 1B;oxysterol-binding protein-related protein 1 varia
Recombinant Proteins
- Rat
- Human
- Mouse
- Mammalian Cells
- HEK293
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| OSBPL1A-4205R | Recombinant Rat OSBPL1A Protein | Mammalian Cells | Rat | His |
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| OSBPL1A-3539HCL | Recombinant Human OSBPL1A 293 Cell Lysate | HEK293 | Human | Non |
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| OSBPL1A-3540HCL | Recombinant Human OSBPL1A 293 Cell Lysate | HEK293 | Human | Non |
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| OSBPL1A-3012H | Recombinant Human OSBPL1A Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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| OSBPL1A-3867R | Recombinant Rat OSBPL1A Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| OSBPL1A-3867R-B | Recombinant Rat OSBPL1A Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| Osbpl1a-4608M | Recombinant Mouse Osbpl1a Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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Involved Pathway
OSBPL1A involved in several pathways and played different roles in them. We selected most pathways OSBPL1A participated on our site, such as Adaptive Immune System,Immune System,MHC class II antigen presentation, which may be useful for your reference. Also, other proteins which involved in the same pathway with OSBPL1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Immune System | TRIM69,ALCAMB,KIF11,SH3RF1,KIF2B,FBXO3,CASPB,LY86,NOD1,PPIAL4A |
| Adaptive Immune System | KIF20A,ACTR1B,MOV10,IFI30,UBE2J2,AP2A2,RNF111,ASB7,KLRB1B,WWP1 |
| MHC class II antigen presentation | RACGAP1,FAM49BA,CTSE,DYNC1LI2,DCTN6,CTSLL,KIF3B,KLC3,CTSO,CTSC |
Protein Function
OSBPL1A has several biochemical functions, for example, cholesterol binding,phospholipid binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by OSBPL1A itself. We selected most functions OSBPL1A had, and list some proteins which have the same functions with OSBPL1A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | MYBPHL,BUD13,ACAA2,MUM1,IFI30,PITPNM1,DEPDC6,DUSP12,HPGDS,MYH11 |
| cholesterol binding | CYP11A1,ERLIN2,ABCA1,CAV1,APOF,OSBPL7,CETP,ERLIN1,APOD,ANXA6 |
| phospholipid binding | SPTB,LRBA,SGIP1,SEC14L2,APOEA,SPTBN2,APOA5,VAMP2,SYT14,PAFAH2 |
Interacting Protein
OSBPL1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OSBPL1A here. Most of them are supplied by our site. Hope this information will be useful for your research of OSBPL1A.
GCNT1;Cenpf;Aurkb;Nfya;BCL6;Rab5b;Eea1;KIFAP3;POLG2
Resources
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References
- Cha, S; Yu, H; et al. Bone Mineral Density-Associated Polymorphisms Are Associated with Obesity-Related Traits in Korean Adults in a Sex-Dependent Manner. PLOS ONE 7:-(2012).
- Thorsen, K; Schepeler, T; et al. Tumor-specific usage of alternative transcription start sites in colorectal cancer identified by genome-wide exon array analysis. BMC GENOMICS 12:-(2011).
