ORC6
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Official Full Name
origin recognition complex, subunit 6 -
Overview
The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis. -
Synonyms
ORC6;ORC6L;origin recognition complex subunit 6;OTTHUMP00000163361
Recombinant Proteins
- Zebrafish
- Human
- Chicken
- Mouse
- Mammalian Cells
- E.coli
- HEK293
- His
- Myc&DDK
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ORC6-11947Z | Recombinant Zebrafish ORC6 | Mammalian Cells | Zebrafish | His |
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| ORC6-2351H | Recombinant Human ORC6, His-tagged | E.coli | Human | His | 275aa |
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| ORC6-5091C | Recombinant Chicken ORC6 | Mammalian Cells | Chicken | His |
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| ORC6-5092C | Recombinant Chicken ORC6 | Mammalian Cells | Chicken | His |
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| ORC6-290H | Recombinant Human ORC6 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| ORC6-3522H | Recombinant Human ORC6 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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| Orc6-4601M | Recombinant Mouse Orc6 Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| ORC6-4955H | Recombinant Human ORC6 protein, GST-tagged | E.coli | Human | GST | 1-252aa |
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Involved Pathway
ORC6 involved in several pathways and played different roles in them. We selected most pathways ORC6 participated on our site, such as Cell cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with ORC6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell cycle | ODF2,CDC25C,CCNB3,RAD9,CCNE2,GADD45G,RBBP4,SMC2,DCTN1,CDK6 |
Protein Function
ORC6 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ORC6 itself. We selected most functions ORC6 had, and list some proteins which have the same functions with ORC6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
ORC6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ORC6 here. Most of them are supplied by our site. Hope this information will be useful for your research of ORC6.
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