OPN5

  • Official Full Name

    opsin 5

  • Overview

    Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This opsin gene is expressed in the eye, brain, testes, and spinal cord. This gene belongs to the seven-exon subfamily of mammalian opsin genes that includes peropsin (RRH) and retinal G protein coupled receptor (RGR). Like these other seven-exon opsin genes, this family member may encode a protein with photoisomerase activity. Alternative splicing results in multiple transcript variants.

  • Synonyms

    OPN5;opsin 5;TMEM13, transmembrane protein 13;opsin-5;dJ402H5.1;neuropsin;Gpr136;G protein-coupled receptor 136;G-protein coupled receptor PGR12;HGNC:21318;PGR12;TMEM13;Transmembrane protein 13;G-protein coupled receptor 136

Recombinant Proteins

  • Mouse
  • Chicken
  • Zebrafish
  • Human
  • Mus musculus
  • Mammalian Cells
  • E.coli
  • HEK293
  • His
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
OPN5-12172M Recombinant Mouse OPN5 Protein Mammalian Cells Mouse His
OPN5-3861C Recombinant Chicken OPN5 Mammalian Cells Chicken His
OPN5-7908Z Recombinant Zebrafish OPN5 Mammalian Cells Zebrafish His
OPN5-919H Recombinant Human OPN5 Mammalian Cells Human His
OPN5-2531H Recombinant Human OPN5 Protein, His-tagged E.coli Human His Met1-Thr181
OPN5-3733H Recombinant Human OPN5 Protein, His (Fc)-Avi-tagged HEK293 Human His&Fc&Avi
OPN5-3733H-B Recombinant Human OPN5 Protein Pre-coupled Magnetic Beads HEK293 Human
OPN5-6400M Recombinant Mouse OPN5 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
OPN5-6400M-B Recombinant Mouse OPN5 Protein Pre-coupled Magnetic Beads HEK293 Mouse
RFL22543HF Recombinant Full Length Human Opsin-5(Opn5) Protein, His-Tagged E.coli Human His Full L. Full Length (1-354)
RFL35382MF Recombinant Full Length Mouse Opsin-5(Opn5) Protein, His-Tagged E.coli Mus musculus His Full L. Full Length (1-377)

    Involved Pathway

    OPN5 involved in several pathways and played different roles in them. We selected most pathways OPN5 participated on our site, such as Class A/1 (Rhodopsin-like receptors),G alpha (i) signalling events,GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with OPN5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Class A/1 (Rhodopsin-like receptors) GPR65,GPR37L1,OXGR1,SSTR5,PYY,CCR7,S1PR3,DRD5,GPR132B,GAL
    Opsins OPN4B,RGS1,OPN4.1,OPN1LW1,OPN1SW1,OPN4,OPN1LW2,RGR,OPN4A
    GPCR ligand binding EMR4,FPR-RS6,RXFP2,GPR120,KISS1,PYYA,PENKB,GNB5A,EMR1,CCL35.1
    GPCR downstream signaling TAS2R3,CNR1,OXGR1A.3,GPR18,OR56A1,AGT,QRFP,INSL5,APLNR,CGA
    G alpha (i) signalling events OXGR1A.2,PTGDR2,CCL35.2,OXGR1A.1,OXGR1,OPN1LW,DRD2,OPN1MW2,FPR-RS4,NMU
    Signal Transduction RGR,LGR6,PYYA,EDN3,CDC42EP3,SKILB,AXL,RNF31,OR10A5,RNF43
    Signaling by GPCR RGS18,ZFPM2B,ADM2A,GPR39,PROKR1A,ARHGEF3,ACKR4,PENK,PLEKHG2,OBSCN

    Protein Function

    OPN5 has several biochemical functions, for example, 11-cis retinal binding,G-protein coupled receptor activity,photoreceptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by OPN5 itself. We selected most functions OPN5 had, and list some proteins which have the same functions with OPN5. You can find most of the proteins on our site.

    Function Related Protein
    photoreceptor activity OPN1MW3,OPN4XB,OPN4.1,TMTOPS2A,OPN1MW1,OPNP,OPN1MW4,TMTOPS3A,VALOPB,OPN1SW1
    G-protein coupled receptor activity NPFFR1L1,SETD6,OLFR474,PARAPINOPSINB,TMTOPS2A,GPR186,PRLHR2A,TACR1A,OPN4XB,OR1A2
    11-cis retinal binding OPN4,RLBP1

    Interacting Protein

    OPN5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OPN5 here. Most of them are supplied by our site. Hope this information will be useful for your research of OPN5.

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