OAS3

  • Official Full Name

    2-5-oligoadenylate synthetase 3, 100kDa

  • Overview

    This gene encodes an enzyme included in the 2, 5 oligoadenylate synthase family.This enzyme is induced by interferons and catalyzes the 2, 5 oligomers of adenosine in order to bind and activate RNase L.This enzyme family plays a significant role in the inhibition of cellular protein synthesis and viral infection resistance.

  • Synonyms

    OAS3;2-5-oligoadenylate synthetase 3, 100kDa;2 5 oligoadenylate synthetase 3 (100 kD);2-5-oligoadenylate synthase 3;p100OAS;p100 OAS;2-5A synthase 3;2-5A synthetase 3;(2-5)oligo(A) synthase 3;(2-5)oligo(A) synthetase 3;2-5oligoadenylate syntheta

Recombinant Proteins

  • Human
  • Mouse
  • Rat
  • E.coli
  • Mammalian Cells
  • HEK293
  • GST
  • His
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
OAS3-1434H Recombinant Human OAS3, GST-tagged E.coli Human GST 1-350aa
OAS3-3742H Recombinant Human OAS3 protein, His-tagged E.coli Human His 1-350 aa
OAS3-11043M Recombinant Mouse OAS3 Protein Mammalian Cells Mouse His
OAS3-4145R Recombinant Rat OAS3 Protein Mammalian Cells Rat His
OAS3-3613HCL Recombinant Human OAS3 293 Cell Lysate HEK293 Human Non
OAS3-3807R Recombinant Rat OAS3 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
OAS3-3807R-B Recombinant Rat OAS3 Protein Pre-coupled Magnetic Beads HEK293 Rat
OAS3-6296M Recombinant Mouse OAS3 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
OAS3-6296M-B Recombinant Mouse OAS3 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    OAS3 involved in several pathways and played different roles in them. We selected most pathways OAS3 participated on our site, such as Hepatitis C,Measles,Influenza A, which may be useful for your reference. Also, other proteins which involved in the same pathway with OAS3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Influenza A TLR4,IFN-a,DNAJC3,PABPN1L,CPSF4,ADAR,OAS1,PABPN1,IRF3,HNRNPUL1
    Measles TNFRSF10D,CCNE2,SLAMF1,TNFSF10,MAP3K7,TLR9,OAS1B,NFKBIA,HSPA8,RAB9A
    Hepatitis C PIK3R5,MAPK12,TNF,CLDN11,TYK2,PPARA,IKBKE,HRAS,IRF1,MAPK10
    Herpes simplex infection HCFC1B,HLA-B,TRAF3,Ifna15,PPP1CAA,CLOCKA,CDC34A,FAS,DAXX,CDC34

    Protein Function

    OAS3 has several biochemical functions, for example, 2-5-oligoadenylate synthetase activity,ATP binding,double-stranded RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by OAS3 itself. We selected most functions OAS3 had, and list some proteins which have the same functions with OAS3. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding ACTB1,UBE2U,FARS2,CAMKVB,MCCC1,PDIK1L,RPS6KA3,XRCC2,BAZ1B,PRKD3
    protein binding MAPK15,HIST1H1E,TTR,STYK1,VPS29,ATP2A2,THBS4,GP1BA,CLINT1,KNG1
    double-stranded RNA binding HMGB1,CLTC,TUBB4B,LSM14A,DGCR8,ADARB1,DDX21,OAS2,EIF2C3,YRDC
    metal ion binding GNA12,DOM3Z,FEZF1,MFNG,APEX1,NEURL1AB,BSN,KLF15,PFKL,ADI1
    2-5-oligoadenylate synthetase activity OAS1A,OASL2,OAS1,OAS2

    Interacting Protein

    OAS3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OAS3 here. Most of them are supplied by our site. Hope this information will be useful for your research of OAS3.

    EIF6;IFRD2;DHX30;MAVS;FTSJ3;PPM1G;CCDC22;TOP1;HIST1H1C;PABPC4;Eea1;ZNF622;GNL3;GTPBP4;LYAR

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