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O3FAR1

  • Official Full Name

    omega-3 fatty acid receptor 1
  • Overview

    GPR120 is a member of the rhodopsin family of G protein-coupled receptors (GPRs). This gene encodes a G protein-coupled receptor (GPR) which belongs to the rhodopsin family of GPRs. The encoded protein functions as a receptor for free fatty acids, including omega-3, and participates in suppressing anti-inflammatory responses and insulin sensitizing. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    GT01;PGR4;GPR120;GPR129;MGC119984;DKFZp686F0824;omega-3 fatty acid receptor 1;OTTHUMP00000032309;OTTHUMP00000032310;G protein-coupled receptor 120;G protein-coupled receptor 129;G-protein coupled receptor 120;G-protein coupled receptor 129;G protein-coupled receptor PGR4;G-protein coupled receptor GT01;G-protein coupled receptor PGR4;G-protein-coupled receptor GT01;omega-3 fatty acid receptor 1;O3FAR1
Cat.# Product name Source (Host) Species Tag Protein Length Price
O3FAR1-4140R Recombinant Rat O3FAR1 Protein Mammalian Cell Rat His
O3FAR1-3802R Recombinant Rat O3FAR1 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
O3FAR1-3802R-B Recombinant Rat O3FAR1 Protein Pre-coupled Magnetic Beads HEK293 Rat

    Involved Pathway

    O3FAR1 involved in several pathways and played different roles in them. We selected most pathways O3FAR1 participated on our site, such as Incretin synthesis, secretion, and inactivation,Metabolism of proteins,Non-odorant GPCRs, which may be useful for your reference. Also, other proteins which involved in the same pathway with O3FAR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Peptide hormone metabolism GPR120,BCHE,CMA1,CPA3,INHA,GRP,ATP6AP2,PCSK2,CPB1,MBOAT4
    Non-odorant GPCRs RRH,BAI2,GPR132,CELSR1,CELSR3,OPN3,GPR15,EMR4
    Incretin synthesis, secretion, and inactivation GPR120,PCSK1,DPP4,CDX2,GPR119,SPCS3,SLC38A8,GRP
    XPodNet - protein-protein interactions in the podocyte expanded by STRING RAVER1,LIMS2,FRAS1,FLII,SMARCD3,Ighg,MTAP1A,OASL2,PKD1,KCP
    Metabolism of proteins TBCD,TIMM10,ADAMTSL1,SPCS3,DAD1,TRAPPC10,FBXW4,FBXW9,DPH3,SFTPBB

    Protein Function

    O3FAR1 has several biochemical functions, for example, G-protein coupled receptor activity,fatty acid binding,lipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by O3FAR1 itself. We selected most functions O3FAR1 had, and list some proteins which have the same functions with O3FAR1. You can find most of the proteins on our site.

    Function Related Protein
    lipid binding GPIHBP1,BPIFB3,ATP5G3,CLINT1,CRABP2A,HSP12,FAM123C,ACBD7,LIPF,NME4
    fatty acid binding FABP7B,FABP1,FABP2,LBFABP,PMP2,ADH5,FABP1B.1,FABP10A,Alb,APOC1
    taste receptor activity TAS2R143,TAS2R140,TAS2R3,TAS2R139,TAS2R7,TAS2R138,TAS2R108,TAS1R3,TAS2R134,TAS1R2
    signal transducer activity TAS2R117,TICAM2,OLFR498,CXCR4A,TAAR10D,OLFCS1,MTNR1AA,TACR1B,TACR3L,CRKL
    G-protein coupled receptor activity FZD9B,TAS2R103,OLFR498,GRM2,TAAR11,OR13A1,TAAR10B,OPN1MW,TAAR7D,OR51B2
    protein binding CD1d1,PPIAL4A,SELPLG,RWDD1,NRL,SCARA3,FGF13,DDX18,NPY1R,CLK4

    Interacting Protein

    O3FAR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with O3FAR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of O3FAR1.

    Resources

    References

    • Fontanesi, L; Bertolini, F; et al. Next Generation Semiconductor Based-Sequencing of a Nutrigenetics Target Gene (GPR120) and Association with Growth Rate in Italian Large White Pigs. ANIMAL BIOTECHNOLOGY 26:92-97(2015).
    • Lager, S; Ramirez, VI; et al. Expression and localization of the omega-3 fatty acid receptor GPR120 in human term placenta. PLACENTA 35:523-525(2014).