NXF2
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Official Full Name
nuclear RNA export factor 2 -
Overview
This gene is one of a family of nuclear RNA export factor genes. It encodes a protein that is involved in mRNA export, is located in the nucleoplasm, and is associated with the nuclear envelope. Alternative splicing seems to be a common mechanism in this gene family. Two variants have been found for this gene. -
Synonyms
NXF2;nuclear RNA export factor 2;cancer/testis antigen 39;CT39;TAP like protein 2;TAPL 2;FLJ20416;TAPL2;OTTHUMP00000023710;OTTHUMP00000023711;OTTHUMP00000023712;TAP-like protein 2;t-complex protein 11 homolog;NXF2B;TAPL-2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NXF2-3621HCL | Recombinant Human NXF2 293 Cell Lysate | HEK293 | Human | Non |
|
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| Nxf2-1874M | Recombinant Mouse Nxf2 Protein, His-tagged | E.coli | Mouse | His | Leu454-Lys685 |
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| NXF2-1977H | Recombinant Human NXF2 Protein, His-tagged | E.coli | Human | His |
|
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| NXF2-2520H | Recombinant Human NXF2 Protein, His-tagged | E.coli | Human | His | Leu391-Ser625 |
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| nxf2-643F | Recombinant Fruit fly nxf2 protein, His&Myc-tagged | E.coli | Fruit fly | His&Myc | 573-841aa |
|
| nxf2-7432F | Recombinant Fruit fly nxf2 protein, His-tagged | Insect cells | Fruit fly | His | 573-841aa |
|
Involved Pathway
NXF2 involved in several pathways and played different roles in them. We selected most pathways NXF2 participated on our site, such as Ribosome biogenesis in eukaryotes,RNA transport,mRNA surveillance pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with NXF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Influenza A | EIF2AK3,PIK3R2,ACTG1,IFNA1,TNFRSF10C,MAPK12,PIK3R1,SLC25A6,PIK3CA,OAS1A |
| RNA transport | POP1,NUP37,RNPS1,RPP25,AAAS,THOC5,EIF1AXB,KPNB1,EIF3I,EIF4G3 |
| mRNA surveillance pathway | FIP1L1,PABPC1L,CPSF2,GSPT2,MSI2A,RNMT,NXF3,PPP1CAB,WIBG,PPP2CA |
| Herpes simplex infection | Hc,CUL1,MHC1UXA2,BLA,TBPL2,PER2,TRAF1,C5,IFNA17,IFNG |
| Ribosome biogenesis in eukaryotes | TCOF1,RPP30,EIF6,RCL1,WDR43,FBLL1,cka2,HEATR1,RPP38,NOP58 |
Protein Function
NXF2 has several biochemical functions, for example, mRNA binding,nucleotide binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NXF2 itself. We selected most functions NXF2 had, and list some proteins which have the same functions with NXF2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| mRNA binding | HNRPLL,TDRD7,DXO,CSTF3,NCBP2,SLBP,NOVA1,MRPL13,NUDT21,CPSF6 |
| nucleotide binding | HNRPLL,UBE2D2A,ATP2A1L,UPF3A,CPEB1B,KIF20B,ARF1L,GMPPAB,RABL6,SETD1B |
| poly(A) RNA binding | MAP4,HNRNPK,XRN2,DHX8,HELZ2,RRP1,AGO3,NKRF,RIMS1,LAS1L |
| protein binding | STX6,HSD17B10,DIS3L,OSBP,AARSD1,LPAL2,THOC1,ANKRD17,IFT27,SDHAF2 |
Interacting Protein
NXF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NXF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NXF2.
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