NUP54
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Official Full Name
nucleoporin 54kDa -
Overview
The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. This gene encodes a member of the phe-gly (FG) repeat-containing nucleoporin subset. -
Synonyms
NUP54;nucleoporin 54kDa;nucleoporin 54kD;nucleoporin p54;54 kDa nucleoporin;MGC13407
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Rat
- E.coli
- Mammalian Cells
- HEK293
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
NUP54 involved in several pathways and played different roles in them. We selected most pathways NUP54 participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with NUP54 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA transport | RANBP2,ALYREF,NUP93,EIF4E2,NUPL1,TPR,SUMO3,EIF2S3Y,SARNP,NUP37 |
Protein Function
NUP54 has several biochemical functions, for example, nucleocytoplasmic transporter activity,protein binding,structural constituent of nuclear pore. Some of the functions are cooperated with other proteins, some of the functions could acted by NUP54 itself. We selected most functions NUP54 had, and list some proteins which have the same functions with NUP54. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| structural constituent of nuclear pore | NUP98,NUP155,NUP205,NUP62CL,TMEM33,NUP133,NUP62L,NUP62,NUP107,NUP153 |
| protein binding | KCTD6,C19orf40,COL18A1,HMGB2,RPL13,MAPK8,PC,ZHX3,ADRB1,PFTK1 |
| nucleocytoplasmic transporter activity | XPO1,NUP107,TPR,NUPL1,NUP214,UPF3A,NUP35,RBM22,TPRB,NUP153 |
Interacting Protein
NUP54 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NUP54 here. Most of them are supplied by our site. Hope this information will be useful for your research of NUP54.
NUP62;NUPL1;HGS;KRT15;IFT20;HAUS1
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References
- Ulrich, A; Partridge, JR; et al. The stoichiometry of the nucleoporin 62 subcomplex of the nuclear pore in solution. MOLECULAR BIOLOGY OF THE CELL 25:1484-1492(2014).
- Solmaz, SR; Blobel, G; et al. Ring cycle for dilating and constricting the nuclear pore. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 110:5858-5863(2013).
