NUP35
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Official Full Name
nucleoporin 35kDa -
Overview
This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is part of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC.
Recombinant Proteins
- Zebrafish
- Mouse
- Human
- Rhesus macaque
- Rat
- Mammalian Cells
- E.coli
- HEK293
- His
- T7
- Non
- DDK
- Myc
- Avi
- Fc
Involved Pathway
NUP35 involved in several pathways and played different roles in them. We selected most pathways NUP35 participated on our site, such as Antiviral mechanism by IFN-stimulated genes,Cell Cycle,Cell Cycle, Mitotic, which may be useful for your reference. Also, other proteins which involved in the same pathway with NUP35 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell cycle | CEP135,HJURP,CCP110,NUF2,CDKN1BA,HDAC2,PLK4,CENPQ,CDK5RAP2,SMAD4 |
| Cellular responses to stress | RBBP4,H1F0,HIF3A,TXN,HIST1H1D,CBX6,POT1A,DYNLL2,TINF2,POT1 |
| Cellular response to heat stress | PTGES3,HSBP1A,DPF1,NUPL2,HSPA14,BAG5,HSPH1,HSPA13,HSPA7,BAG3 |
| Cytokine Signaling in Immune system | FRS2B,NEFLB,IRF9,PEA15A,MX2,GBP5,WDR83,IFIT10,EGR1,PELI3 |
| Antiviral mechanism by IFN-stimulated genes | NUP50,EIF4G1,EIF4G2,IFIT8,EIF4G2A,MX2,USP18,KPNA4,EIF4A2,NUPL2 |
| Export of Viral Ribonucleoproteins from Nucleus | NUPL2,DPF1,NUP50 |
| Disease | CPSF4,RBP1,OPN1MW,FKBP1A,ELL,FDX1L,TH1L,AP2B1,HEY2,SFTPB |
| Cell Cycle, Mitotic | FGFR1OP,ODF2B,NUMA1,MCM8,E2F4,CENPL,AHCTF1,TUBG1,CDKN1B,HAUS2 |
Protein Function
NUP35 has several biochemical functions, for example, nucleocytoplasmic transporter activity,phospholipid binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NUP35 itself. We selected most functions NUP35 had, and list some proteins which have the same functions with NUP35. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | MS4A3,SH2B1,TAF2,SIAH1A,TFAM,PRF1,CDK5R1,DNAI1,C4BP,MITD1 |
| phospholipid binding | AMPH,SMURF1,FABP1,ANXA1,LPAR3,ARHGAP44,PLEKHA3,HIP1RB,LC3,ANXA5 |
| nucleocytoplasmic transporter activity | TPRB,NUP214,NUP107,NUP160,NUP54,TPR,RBM22,XPO1,NUP133,NUP153 |
| single-stranded DNA binding | TTC6,ERCC4,MCM4,SSBP3B,RBMS1,HSPD1,SSBP3A,PMS1,NABP1,LONP1 |
Interacting Protein
NUP35 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NUP35 here. Most of them are supplied by our site. Hope this information will be useful for your research of NUP35.
KCTD9;saicar;PKM;AHCTF1;v-bcl-2;Kifc5b;NUP153;NUP107;UBE2I;Ube2i;KPNB1;Nup98;Nup214;Nup107;Rcc1;SEH1L;Nup155;NUPL1
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References
- Eisenhardt, N; Redolfi, J; et al. Interaction of Nup53 with Ndc1 and Nup155 is required for nuclear pore complex assembly. JOURNAL OF CELL SCIENCE 127:908-921(2014).
- Vollmer, B; Schooley, A; et al. Dimerization and direct membrane interaction of Nup53 contribute to nuclear pore complex assembly. EMBO JOURNAL 31:4072-4084(2012).
