NUDT9
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Official Full Name
nudix (nucleoside diphosphate linked moiety X)-type motif 9 -
Overview
The protein encoded by this gene belongs to the Nudix hydrolase family. Nudix boxes are found in a family of diverse enzymes that catalyze the hydrolysis of nucleoside diphosphate derivatives. This enzyme is an ADP-ribose pyrophosphatase that catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. It requires divalent metal ions and an intact Nudix motif for enzymatic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. -
Synonyms
NUDT9;nudix (nucleoside diphosphate linked moiety X)-type motif 9;ADP-ribose pyrophosphatase, mitochondrial;MGC3037;mitochondrial;Adenosine diphosphoribose pyrophosphatase;ADP ribose diphosphatase;ADP ribose phosphohydrolase;ADP ribose pyrophosphatase, mitochondrial precursor;ADP-ribose diphosphatase;ADP-ribose phosphohydrolase;ADP-ribose pyrophosphatase;ADPR PPase;ADPR-PPase;EC 3.6.1.13;Nucleoside diphosphate linked moiety X motif 9;Nucleoside diphosphate-linked moiety X motif 9;Nudix motif 9;NUDT9_HUMAN;ADP-ribose pyrosphosphatase NUDT9;nucleoside diphosphate linked moiety X-type motif 9;NUDT10
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Rhesus macaque
- Rat
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
NUDT9 involved in several pathways and played different roles in them. We selected most pathways NUDT9 participated on our site, such as Purine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with NUDT9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Purine metabolism | AMPD3B,NME4,DGUOK,PKM,POLR2J,POLR3D,POLR3F,NPR1A,NT5C3B,ADK |
Protein Function
NUDT9 has several biochemical functions, for example, ADP-ribose diphosphatase activity,ADP-sugar diphosphatase activity,adenosine-diphosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NUDT9 itself. We selected most functions NUDT9 had, and list some proteins which have the same functions with NUDT9. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| adenosine-diphosphatase activity | ENTPD2,SLC25A42 |
| ADP-ribose diphosphatase activity | ADPRM,NUDT14,TRPM2,NUDT5 |
| ADP-sugar diphosphatase activity | NUDT5 |
Interacting Protein
NUDT9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NUDT9 here. Most of them are supplied by our site. Hope this information will be useful for your research of NUDT9.
MDM2;EPHA2
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