NUDT6

  • Official Full Name

    nudix (nucleoside diphosphate linked moiety X)-type motif 6

  • Overview

    This gene overlaps and lies on the opposite strand from FGF2 gene, and is thought to be the FGF2 antisense gene. The two genes are independently transcribed, and their expression shows an inverse relationship, suggesting that this antisense transcript may regulate FGF2 expression. This gene has also been shown to have hormone-regulatory and antiproliferative actions in the pituitary that are independent of FGF2 expression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

  • Synonyms

    NUDT6;nudix (nucleoside diphosphate linked moiety X)-type motif 6;nucleoside diphosphate-linked moiety X motif 6;FGF AS;FGF2AS;gfg;gfg 1;antisense basic fibroblast growth factor;GFG1;GFG-1;ASFGF2;FGF-AS

Recombinant Proteins

  • Mouse
  • Rat
  • Zebrafish
  • Human
  • Mammalian Cells
  • HEK293
  • His
  • Non
  • Flag
  • His&Fc&Avi
  • Myc&DDK

    Involved Pathway

    NUDT6 involved in several pathways and played different roles in them. We selected most pathways NUDT6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NUDT6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    NUDT6 has several biochemical functions, for example, growth factor activity,hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NUDT6 itself. We selected most functions NUDT6 had, and list some proteins which have the same functions with NUDT6. You can find most of the proteins on our site.

    Function Related Protein
    hydrolase activity LIPM,MCPT2,CHD8,NUDT17,MEP1A.1,Casp3,PLCD1A,TMPRSS7,DUB1,GNPDA1
    growth factor activity NRTN,CDNF,MACC1,BMP2,INHA,GMFB,PDGFD,COL20A1,IL6,EGF

    Interacting Protein

    NUDT6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NUDT6 here. Most of them are supplied by our site. Hope this information will be useful for your research of NUDT6.

    UBA1;UBE2N;UBE2V1;SCHIP1

    Resources

    References

    • Albayrak, O; Putter, C; et al. Common obesity risk alleles in childhood attention-deficit/hyperactivity disorder. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS 162B:295-305(2013).
    • Wilson, GRS; Morton, JD; et al. The locus for an inherited cataract in sheep maps to ovine chromosome 6. MOLECULAR VISION 18:1384-1394(2012).

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